Press, Neil, Paterson, Andrew, St John-Campbell, Sahra, Mahon, Mary and Frost, Christopher (2015) Catalytic meta-selective C-H functionalization to construct quaternary carbon centres. Chemical Communications, 51 (64). ISSN 1359-73451364-548X

Abstract

A catalytic meta-selective C-H functionalization of 2-phenylpyridines using a range of tertiary halides is described. The protocol is simple to perform and usees commercially available reagents to construct challenging quaternary carbon centres in a regioselective manner. Preliminary studies suggest the C-H functionalization proceeds trhough a radical process directed via a remote sigma activation.

Item Type:	Article
Date Deposited:	26 Apr 2016 23:45
Last Modified:	26 Apr 2016 23:45
URI:	https://oak.novartis.com/id/eprint/25922