Bentz, J, O'Connor, MP, Bednarczyk, D, Coleman, J, Lee, C, Palm, J, Pak, YA, Perloff, ES, Reyner, E, Balimane, P, Brannstrom, M, Chu, X, Funk, C, Guo, A, Hanna, I, Heredi-Szabo, K, Hillgren, K, Li, L, Hollnack-Pusch, E, Jamei, M, Lin, X, Mason, AK, Neuhoff, S, Patel, A, Podila, L, Plise, E, Rajaraman, G, Salphati, L, Sands, E, Taub, ME, Taur, JS, Weitz, D, Wortelboer, HM, Xia, CQ, Xiao, G, Yabut, J, Yamagata, T, Zhang, L and Ellens, H (2013) Variability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision Criteria. DRUG METABOLISM AND DISPOSITION. pp. 1347-1366.

Item Type:	Article
Additional Information:	pubid: 245 nvp_institute: NIBR contributor_address: Drexel Univ, Dept Biol, Philadelphia, PA 19104 USA ; Optivia, Biotechnol, Menlo Pk, CA USA ; Pfizer Inc, Dept Pharmacokinet Dynam & Metab, San Diego, CA USA ; CVGI iMed DMPK, AstraZeneca R&D Molndal, Innovat Med, Molndal, Sweden ; Eli Lilly & Co, Lilly Res Labs, Investigat Drug Disposit, Indianapolis, IN 46285 USA ; BD GentestSM Contract Res Serv, BD Biosci Discovery Labware, Woburn, MA USA ; Bristol Myers Squibb, Pharmaceut Candidate Optimizat, Bristol Myers Squibb, Princeton, NJ USA ; Merck & Co Inc, Dept Pharmacokinet Pharmacodynam & Drug Metab, Rahway, NJ USA ; F Hoffmann La Roche, Nonclin Drug Safety, Basel, Switzerland ; Hoffmann La Roche, Nonclin Drug Safety, Nutley, NJ USA ; Novartis Inst BioMed Res, E Hanover, NJ USA ; SOLVO Biotechnol, Budapest, Hungary ; Absorpt Syst LP, Exton, PA USA ; Simcyp, Sheffield, S Yorkshire, England ; Novartis Inst BioMed Res, Cambridge, MA USA ; Boehringer Ingelheim Pharmaceut Inc, Drug Metab & Pharmacokinet, Ridgefield, CT USA ; Genentech Inc, Dept Drug Metab & Pharmacokinet, San Francisco, CA 94080 USA ; CellzDirect Life Technol Ltd, Austin, TX USA ; Biogen Idec Inc, Drug Metab & Pharmacokinet, Cambridge, MA USA ; Eisai Inc, Andover, MA USA ; R&D DSAR Drug Disposit FF, Sanofi Aventis, Frankfurt, Germany ; TNO, NL-3700 AJ Zeist, Netherlands ; Millennium Pharmaceut Inc, Cambridge, MA USA ; Merck Serono, Inst Drug Metab & Pharmacokinet, Grafing, Germany ; US FDA, Off Clin Pharmacol, Off Translat Sci, Ctr Drug Evaluat & Res, Silver Spring, MD USA ; Drug Metab & Pharmacokinet, King Of Prussia, PA USA ; Drexel Univ, Dept Biol, Philadelphia, PA 19104 USA; Bentz, J; Drexel Univ, Dept Biol, Philadelphia, PA 19104 USA
Date Deposited:	13 Oct 2015 13:12
Last Modified:	13 Oct 2015 13:12
URI:	https://oak.novartis.com/id/eprint/22050