Woodward, Hannah, Smith, Nichola and Gallagher, Timothy (2010) Exo-Glycals: Versatile Intermediates in the Synthesis of 1,1-Disubstituted C Glycosides. Synlett (6). pp. 869-872. ISSN 0936-5214

Abstract

The synthesis of 1,1-disubstituted C-glycosides 15, 18 and 21 containing amino and ester moieties at what is formally the anomeric site is described. Petasis olefination reaction of pyranosyl lactones 5-7 provided exo-glycals 8-10 which underwent regioselective azidoselenation and subsequent radical-mediated C-glycoside formation.

Item Type:	Article
Related URLs:	http://dx.doi.org/10.1055/s-0029-1219560
Additional Information:	Author can archive post-print (ie final draft post-refereeing) subject to 12 month embargo on institutional repository; Publisher's version/PDF cannot be used
Keywords:	C-glycosides; azidoselenation; Petasis olefination
Related URLs:	http://dx.doi.org/10.1055/s-0029-1219560
Date Deposited:	13 Oct 2015 13:16
Last Modified:	13 Oct 2015 13:16
URI:	https://oak.novartis.com/id/eprint/2149