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Chemical Constituents from Gouania longipetala and Glyphaea brevis

Ekuadzi, E., Dickson , R.A., Fleischer, T.C., Amponsah, I.K., Pistorius, Dominik and Oberer, Lukas (2014) Chemical Constituents from Gouania longipetala and Glyphaea brevis. Natural Product Research, 28 (15). pp. 1210-1213.

Abstract

Five compounds were isolated altogether from the two medicinal plants. Glycerol monovalerate (1), palmarumycin BG1 (2), and de-O-methyllasiodiplodin (3) were isolated from G. longipetala. Additionally, epicatechin (4) and its’ dimer procyanidin B2 (5) were isolated from the stem bark of G. brevis. Their structures were elucidated by spectroscopic experiments. 1 displayed moderate antibacterial activities with the least MIC of 125 µg/mL against E. faecalis. In addition, 1 reduced DPPH with an IC50 value of 102.34 µg/mL.

Item Type: Article
Keywords: glycerol monovalerate; palmarumycin BG1; de-O-methyllasiodiplodin, epicatechin, procyanidin B2; antibacterial; antioxidant
Date Deposited: 13 Oct 2015 13:13
Last Modified: 13 Oct 2015 13:13
URI: https://oak.novartis.com/id/eprint/21160

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