Simon, Oliver, Bates, Roderick W. and Tang, Chi H. (2014) A synthesis of 5-Hydroxysedamine using Hydroformylation. Tetrahedron, 70 (12). pp. 2134-2140. ISSN 00404020

Abstract

A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hydroxy group.

Item Type:	Article
Keywords:	5-hydroxysedamine, hydroformylation, dihydroxylation, allylation, stereoselectivity
Date Deposited:	27 Apr 2016 23:45
Last Modified:	27 Apr 2016 23:45
URI:	https://oak.novartis.com/id/eprint/20299