Kawanami, Toshio, Karns, Alexander, Adams, Christopher and Serrano-Wu, Michael (2013) Efficient preparation of Ellman’s imines from trifluoromethyl ketones promoted by zirconium tert-butoxide. Tetrahedron Letters.

Abstract

Zirconium-mediated imine formation reaction of trifluoromethyl ketones with chiral N-tert-butylsulfinamide is described. The efficiency of this protcol was superior to the standard titanium based procedure especially for sterically demanding trfluoromethyl ketones.

Item Type:	Article
Date Deposited:	13 Oct 2015 13:13
Last Modified:	13 Oct 2015 13:13
URI:	https://oak.novartis.com/id/eprint/10854