Kinase-Kernel Models: Accurate Chemogenomic Method for the Entire Human Kinome
Tools
Tian, Li, Mukherjee, Prasenjit and Martin, Eric (2013) Kinase-Kernel Models: Accurate Chemogenomic Method for the Entire Human Kinome. Molecular Informatics.
Official URL: http://onlinelibrary.wiley.com/journal/10.1002/(IS...
Abstract
Chemogenomic kinase-kernel virtual screening models interpolate between very accurate, empirically-trained Profile-QSAR models of the nearest binding-site homologues with IC50 assay data. Between them, activity has been predicted for the entire human kinome.
Item Type: | Article |
---|---|
Keywords: | Kernel, Chemogenomics, Kinomics, Virtual screening, Chemoinformatics |
Date Deposited: | 27 Apr 2016 23:45 |
Last Modified: | 27 Apr 2016 23:45 |
URI: | https://oak.novartis.com/id/eprint/10279 |