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[Multicenter study on the litholytic effect of ursodeoxycholic acid. 30 cases].

Voirol, M and Stalder, G A and Fasel, J and Sechaud, Romain and Desbaillets, L G and Kapp, F and Krieg, P and Aenishänslin, H W and Wyss, G (1983) [Multicenter study on the litholytic effect of ursodeoxycholic acid. 30 cases]. Schweizerische medizinische Wochenschrift, 113 (17). pp. 643-645. ISSN 0036-7672

Abstract

In the context of a cooperative clinical trial carried out in the Cantons of Basel and Vaud, Switzerland, the litholytic effect of ursodeoxycholic acid (Ursochol) in a daily dose of 9 mg/kg was investigated in 42 patients with radiotransparent gallstones. The litholytic effect was evident in 22 (73%) of the 30 patients followed up for a maximum period of 1 year. Complete dissolution of gallstones was obtained in 40% of cases. In addition, ursodeoxycholic acid significantly reduced (p less than 0,001) the dyspeptic-painful symptoms and the number of biliary colics. Tolerance was excellent. In particular, no cases of diarrhea were observed.

Item Type: Article
Date Deposited: 28 Jan 2012 00:45
Last Modified: 01 Feb 2013 00:46
URI: https://oak.novartis.com/id/eprint/5615

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