Browse views: by Year, by Function, by GLF, by Subfunction, by Conference, by Journal

Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial.

Nisbet-Brown, Eric and Olivieri, Nancy F and Giardina, Patricia J and Grady, Robert W and Neufeld, Ellis J and Sechaud, Romain and Krebs-Brown, Axel and Anderson, Judith and Alberti, Daniele Maria and Sizer, Kurt and Nathan, David G (2003) Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet, 361 (9369). pp. 1597-1602. ISSN 0140-6736

Abstract

Transfusional iron overload is a potentially fatal complication of the treatment of thalassaemia. We aimed to investigate short-term efficacy, pharmacokinetic/pharma- codynamic (PK/PD) relations, and safety of ICL670, a novel, tridentate, orally active iron chelator.

Item Type: Article
Related URLs:
Related URLs:
Date Deposited: 28 Jan 2012 00:45
Last Modified: 01 Feb 2013 00:46
URI: https://oak.novartis.com/id/eprint/5608

Search

Email Alerts

Register with OAK to receive email alerts for saved searches.