B

Brown, Alan, Friedrichs, Gregory, Tang, Hai-Ming, Weber, Valerie, Traebert, Martin, Yao, Nancy and Yan, Gan-Xin Electrophysiological changes observed in the rabbit ventricular wedge assay and in human-induced pluripotent stem-cell derived (iPS) cardiomyocytes correlated with severe arrhythmia observed in vivo, whereas standard in vitro ion channel assays were not predictive of effects seen.

C

Chase, John, Busa, Michael and Sirard, John Sleep Measurement Using Wrist-Worn Accelerometer Data Compared to Polysomnography.

D

de Paula Souza, Joyce, Jeanneau, Karine, Allard, Cyril, Angevaare, Eline, Aschenbrenner, Dominik, Bassi, Zuni, Bodendorf, Ursula, Demarco, Benjamin, Farady, Christopher, Gounarides, John, Killmer, Saskia, Kovarik, Jiri, Pfister, Sabina, Yin, Hong2, Hepprich, Matthias, Fischer, Justus S., Ratnarasa, Vithushan, Böni-Schnetzler, Marianne, Meier, Daniel T., Wieczorek, Grazyna and Donath, Marc Y. NLRP3 and caspase-1 inhibitors block NLRP3 inflammasome activity in peripheral blood monocytes of T2D patients and healthy controls.

E

Eifler, Nora, Rossi, Sara-1, Bitar, Malak, Tedeschi, Concetta, Be, Celine and Duvnjak, Marieta Effective methods for assessing the saturation concentration of an API in a topical formulation.

Even, Caroline , Wang, Hung-Ming , Li, Shau-Hsuan, Ngan, Roger , Dechaphunkul, Arunee , Zhang, Li , Yen, Chia Jui , Chan, Po Chung , Chakrabandhu, Somvilai , Ma, Brigette , Tanasanvimon, Suebpong , Lee, Victor , Lou, Pei-Jen , Li, Zujun , Spira, Alexander , Sukari, Ammar , Guigay, Joël , McCune, Steve , Wan-Teck Lim, Darren , Yongjian , Sun, Szpakowski, Sebastian, Yao, Yao, Fan, Oliver and Manenti, Luigi Phase II study of spartalizumab (PDR001) vs chemotherapy in patients with recurrent/metastatic nasopharyngeal cancer.

K

Ke, Xiaobo and Porter, Jeffrey Identification of Bacterial Metabolites that Modulate Endoplasmic Reticulum Stress.

O

O'Donnell, Chris Genomics and Nucleic Acid Therapeutics in Prevention & Treatment of Cardiometabolic Disease: A View from Pharma.

P

Phulera, Swastik, Weihofen, Wilhelm, Whicher, Jonathan, Khoshouei, Maryam and Schwalen, Christopher Cryo-EM studies on Nav Channel - modulator complexes.

R

Renner, Magdalena, Cowan, Cameron, Gross-Scherf, Brigitte, Goldblum, David, Krol, Jacek, Szikra, Tamas, Papasaikas, Panagiotus, Munz, Martin, Cuttat-Theurillat, Rachel, Waldt, Annick, Diggelmann, Roland, Patino-Alvarez, Claudia, Gerber-Hollbach, Nadine, Schuierer, Sven, Srdanovic, Aldin, Balogh, Marton, Pascal, Hasler, Kusnyerik, Akos, Szabo, Arnold, Stadler, Michael, Hierlemann, Andreas, Scholl, Hendrik, Roma, Guglielmo, Nigsch, Florian and Roska, Botond Cell types of the human retina and its organoids at single cell resolution: developmental convergence, transcriptional identity, and disease map.

Rentel, Claus, Gaus, Hans, Bradley, Kym, Luu, Nhuy, Kolkey, Kimmy, Mai, Bao, Madsen, Mark, Pearse, Megan, Bock, Brandon and Capaldi, Daniel Assay, Purity, and Impurity Profile of Phosphorothioate Oligonucleotide Therapeutics by Ion Pair-HPLC-MS. J.O.C.

S

Springer, Clayton and Gora, Jacob Self driving chemical space exploration.

U

Ulrich, Peter MEB/NC3Rs Questionnaire on the optimal duration of non-clinical studies to assess the safety of monoclonal antibodies: Building an evidence-based approach to justify the duration of longer-term toxicity studies with monoclonal antibodies. Journal will be determined after data evaluation.

V

Vicente Gabarda, Sergio, Tiedt, Ralph, Zhao, Sylvia, Myers, Andrea and Kirsilae, Tiina A phase Ib/II, open-label, multicenter study of INC280 in combination with buparlisib in adult patients with recurrent glioblastoma.