Items where Year is 2025
B
Beckmann, Nicolau (2025) Neurobiomarkers: Basic Aspects and their Relevance in Nonclinical Studies. Experimental and Toxicologic Pathology. ISSN 0192-62331533-1601
Benjamin, Solomon, Daniel, Tan, Gilberto, de Castro Jr, Manuel, Cobo, Marina, Chiara Garassino, Jun, Zhang, Bruce, Johnson, Jay, Lee, Pilar, Garrido, Butler, Andrew, Pelletier, Marc, Savchenko, Alexander, Ji, Lexiang, Jan C., Brase, Rafael, Caparica, Demanse, David, Wu, Jincheng, Bossen, Claudia and Tony, Mok (2025) The Impact of the Tumor Microenvironment on the Effect of IL-1β Blockade in NSCLC: Biomarker Analyses from CANOPY-1 and CANOPY-N Trials. Cancer research communications. ISSN 2767-9764
Bonelli, Mirko, Di Stefano, Mauro and Allémann, Eric (2025) Rational design and analytical characterization of self-assembling poly(N-isopropylacrylamide) and poly(2-alkyl-2-oxazoline) hyaluronic acid copolymers. International journal of pharmaceutics, 671. p. 125250. ISSN 1873-3476
Brett D, Akana-Schneider, Julianna M, Mouat, Zhang, Sisi, Michelle, Akana, Wu, Bin-3 and Daniel J, Weix (2025) Translation of Nickel-Catalyzed C(sp2)-C(sp3) Cross-Electrophile Coupling to Non-Amide Solvents. Organic Letters. ISSN 1523-70601523-7052
Burmeister-Getz, Elise, Niglis, Severine, Papadimitriou, Athanasia, Statelova, Marina, Ren, Xiaojun, Nakhla, Keroles, Sharaby, Sherif, Tariq, Muzammil, Garbuio, Luca and Bakhsh, Sumerah (2025) Predicting and Confirming Bioequivalence of Alpelisib Oral Granules and Tablets for Patients With PIK3CA-Related Disorders. AAPS PharmSciTech, 26 (5). pp. 121-135. ISSN 1530-9932
C
Colman, Karyn, Funk, Kathleen A, Boyle, Michael, Brennan, Sebastian, Cain, Gary, Colleton, Curtis, Morton, Laura Dill, Giusti, Anna Maria, Jacquinet, Eric, LaFranco, Lisa, McKinney, LuAnn, Neyens, Elizabeth, Romeike, Annette, Hayashi, Shim-mo, Vahle, John L and Tomlinson, Lindsay (2025) Scientific and Regulatory Policy Committee Points to Consider* for Determining and Reporting Cause of Death/Moribundity in Non-Rodent Species in Toxicity Studies. Experimental and Toxicologic Pathology. p. 1926233251321781. ISSN 0192-62331533-1601
Cummings, Beryl B, Bouchard, Page R, Milton, Mark N, Moesta, Peter F, Ramanan, Vyas, Trauger, John, Maratos-Flier, Eleftheria, Voznesensky, Andrei, Splawski, Igor, Nimonkar, Amitabh, DiPetrillo, Keith, LaSala, Daniel, Pan, Meihui, Flaherty, Meghan, Huet, Francois, Sahambi, Sukhdeep, Dong, Jijun, Knee, Deborah, Cebe, Regis, Huber, Thomas, Lehrer-Graiwer, Joshua, Juliano, Rebecca A and Weiss, Ethan J (2025) An ANGPTL4 inhibitory antibody safely improves lipid profiles in non-human primates. EBioMedicine. p. 105748. ISSN 2352-3964
D
Daizadeh, Nadia, Chen, Jie, Lee, Hana, Rockhold, Frank, Potter, Andrew, Shen, Yuan-Li, Wang, Hongwei, Zhao, Jing, Pang, Herbert, Kirk, Jennifer, He, Weili, Lu, Ying, Zhao, Jing and Di, Junrui (2025) Decentralized Clinical Trials in the Era of Real-World Evidence: A Statistical Perspective. Clinical and translational science, 18 (2). e70117. ISSN 1752-8062
Darstein, Christelle, Yang, Yiqun, Kapoor, Shruti, Dasgupta, Kohinoor, Hoch, Matthias, Grosch, Kai and Sy, Sherwin (2025) Population pharmacokinetic modeling of asciminib in support of exposure-response and ethnic sensitivity analyses in patients with chronic myeloid leukemia. Cancer chemotherapy and pharmacology, 95 (1). p. 39. ISSN 1432-0843
Delmas, Cecile, Sager, Emine, Henry, Christelle, Hassiepen, Ulrich, Skaanderup, Philip and Frings-Kerschgens, Isabel (2025) Reversible Covalent Reactions of Aldehydes and Salicylaldehydes Using a Lysine-Model Substrate. Chimia, 79 (3). pp. 152-157. ISSN 0009-4293
Denefeld, Blandine, Hajduk, Joanna, Kern, Wolfram and Griaud, Francois (2025) Revealing Unpredicted Aspartic Acid Isomerization Hotspots by Probing Diagnostic Fragmentation Propensities in Top-Down and Middle-Down Mass Spectrometry. Journal of the American Society for Mass Spectrometry. ISSN 1879-1123
Dhaval, Gohil, Surigi, Pavan Kalyan, Bhandarkar, PRATIMA, Gosula, Venkatrami Reddy, Clarke, Adrian, Williams, Stuart, Bhutani, Hemant and Kurmi, Moolchand (2025) Investigation of Silanol Catalyzed Generation of Cyclopenta[c]Pyrrole Derivative Artifact Peaks During RP-HPLC Impurity Profiling. SEPARATION SCIENCE PLUS, 8 (4). e70033. ISSN 2573-18152573-1815
Diez, Jonas and Meisinger, Fabio (2025) jGBM Freiburg erhält exclusive Einblicke beim Pharmakonzern Novartis in Basel. Biospektrum, 31 (1). p. 80. ISSN 0947-0867
Dodd, Stephanie, Vulic, Katarina, Harlacher, Cornelius, Statelova, Marina, Werthmueller, Dominic, Pelis, Ryan, Loisios Konstantinidis, Ioannis, Hingle, Martin, Bal, Gobardhan and Pawel, Bigos (2025) Improving accuracy in food effect Predictions: Application of In-Vitro absorption experiments as a useful tool for the evaluation of ten drug products. European journal of pharmaceutics and biopharmaceutics, 211 (114722). ISSN 09396411
Dubost, Valerie, Wuersch, Kuno, Penraat, Kelley, Wekkeli, Anja, Ramakrishna, Ramprasad, Piequet, Aline, Greiner, Geraldine, Jivkov, Magali, Erard, Esther, Hansen, Regine, Brees, Dominique, Hartmann, Andreas, Balavenkatraman, Kamal Kumar and Nunes, Jairo (2025) Characterizing Antisense Oligonucleotide-Induced Histopathology Findings in Spinal Cord of Mauritius Cynomolgus Monkeys by Molecular Localization Investigation. Toxicologic pathology, 53 (1). pp. 95-106. ISSN 1533-1601
F
frommelt, fabian, ladurner, rene, goldmann, ulrich, wolf, gernot, ingles-prieto, alvaro, lineiro-retes, eva, gelova, zuzana, hopp, ann-katrin, christodoulaki, eirini, teoh, Shao, leippe, philipp, rebsamen, manuele, lindinger, sabrina, serrano, iciar, onstein, svenja, limek, christoph, barbosa, barbara, panttielieieva, anastasiia, dvorak, vojtech, hannich, j.thomas, mocking, tamara, ooms, jasper, Sansig, Gilles, Ijzerman, Adriaan, heitman, laura, sykacek, peter, Reinhardt, Juergen, mueller, andre, wiedmer, tabea, superti-furga, giulio and Schoenbett, Julian (2025) The solute carrier superfamily interactome. Molecular systems biology, 12 (2025). pp. 1-29.
G
Gallou, Fabrice (2025) Adding Value to Terpenes: Copper-Catalyzed Oxidation of α-Pinene in Water under Micellar Conditions. green chemistry, 27. pp. 3178-3185.
Gallou, Fabrice (2025) Finding suitable solvents for the green transformation. RSC Sustainability.
Gaskill, B.N., Davis, H., Gosselin, R.P., Garner, J.P., Radcliffe, J.S., Robbins, L.A. and Pritchett-Corning, K.R. (2025) Behavioral or nutritional drive: which motivation affects rates of food grinding in CD1 mice? Applied Animal Behaviour Science, 284. p. 106533. ISSN 01681591
Gellermann, Gerald, Mischo, Andre, Koeck, Rainer and Kirsch, Stephan (2025) Do Patient Needs Define Biologic Product Specifications? Bioprocess Online.
Glowienke, Susanne (2025) Intermediates data sharing - contribution for 2025. Vitic database.
Gu, Helen, Sechaud, Romain, Hanna, Imad, Pelis, Ryan and Einolf, Heidi (2025) Physiologically Based Pharmacokinetic Modeling of Midostaurin and Metabolites at Steady-state to Bridge Drug Interaction Scenarios In Lieu of Clinical Trials. Drug metabolism and disposition (53). ISSN Drug Metabolism and Disposition 100036
Guffroy, Magali, Arndt, Tara, Barale-Thomas, Erio, Bolin, Susan, Grevot, Armelle, Ibanes, Joelle, Laing, Steven T., Leach, Michael W., Meindel, Mandy, Palazzi, Xavier, Ramaiah, Lila, Schwartz, Julie and Johnson, Robert L. (2025) Scientific and Regulatory Policy Committee Points to Consider: Proposal and Recommendations to Reduce Euthanasia of Control Nonhuman Primates in Nonclinical Toxicity Studies. Toxicologic pathology.
H
Hillger, Frank, Keller, Hansjörg, Alave Reyes-Furrer, Angela, Melly, Stefan, Boesch, Julian, Seddik, Sabrina, Pierrel, Eliane, Bello, Fiona, Scharenberg, Meike, Leber, Xavier Charles, Hug, Christian, Vicart, Axel, Greiner, Geraldine, Meyer, Angelika, Cobos-Correa, Amanda, Kaufmann, Markus, Aschenbrenner, Dominik, Allard, Cyril, Delucis-Bronn, Corinne, Killmer, Saskia, Hils, Lukas, Rothen, Julian, Lemire, Sophie, Altorfer, Marc, Lambert, Christian, Bepperling, Alexander, Doelemeyer, Arno, Accart Gris, Nathalie, Couttet, Philippe, Parker, Christian, Rooks, Daniel, Kneissel, Michaela and Summermatter, Serge (2025) Exercise-Induced Myostimulin Enhances Muscle Function in Health and Disease. Proceedings of the National Academy of Sciences of the United States of America PNAS..
Hingle, Martin, Arora, Sumit, Pepin, Xavier, Jamei, Masoud, Sharma, Pradeep, Heimbach, Tycho, Wagner, Christian, Bransford, Philip, Kollipara, Sivacharan, Ahmed, Tausif, Dallmann, Andre, Scherholz, Megerle, Stamatis, Stephen, Cano-Vega, Mario, Mistry, Nena, Tannergren, Christer, Borges, Luiza, Stillhart, Cordula, Rullo, Gregory, Mackie, Claire, Mitra, Amitava, Kushner, Joseph, Jain, Krutika Meena Harish and Polli, James (2025) Development of a Physiologically Based Biopharmaceutics Model (PBBM) Report Template: Considerations for Improved Quality in View of Regulatory Submissions. Molecular Pharmaceutics. A-L. ISSN 1543-8384
I
Iyer, Shwetha and Lee, Cameron (2025) Formulation and Characterization of Bevacizumab Encapsulated Poly (D, L-Lactide-co-glycolide) and Polycaprolactone microspheres. Drug delivery and translational research..
J
Jaeger, Seiji (2025) High Performance Countercurrent Membrane Purification for HCP depletion in biologics. High Performance Countercurrent Membrane Purification for HCP depletion in biologics.
James, Alexander David, Lanshoeft, Christian, Steeno, Gregory S, Spracklin, Douglas K, You, Zhiping, Sharma, Raman, Li, Xue-Qing, Andersson, Linda, Piel, Isabel, Webb, Alison, Doyle, Janine M, Laboureur, Laurent, Da Violante, Georges, Rizzo, David and Siegrist, Yves Martin (2025) Cross-industry demonstration of the validity of the mixed matrix method for the assessment of cross-species exposure coverage of human circulating drug metabolites. Drug metabolism and disposition: the biological fate of chemicals, 53 (3). p. 100041. ISSN 1521-009X
Jones, Byron, Berlin, Conny, Ziegler, Lauren, Sturchler, Christine, Picci, Marie, Martinez, Clemence, Zhou, Mo, Garcia Baena, Irene, Cook, Nigel, Gaunt, Harriet, Mason, Brad, Hamerlijnck, Dominique and Yoshiyama, Majima (2025) Designing a Patient Preference Study on Subcutaneous Medical Devices: Incorporating Health Authority Scientific Advice and Patient Perspectives. Therapeutic innovation & regulatory science.
K
Kavanagh, David, Barratt, Jonathan, Schubart Wellensiek, Anna, Webb, Nicholas, Meier, Matthias and Fakhouri, Fadi (2025) Factor B as a therapeutic target for the treatment of complement-mediated diseases. Frontiers in immunology, 16. p. 1537974. ISSN 1664-3224
Kraemer, Yannick, Stephens, Alexander, Jón, Atiba Buldt, Aurelius, Young, Holder, Lauren and Cody, Ross Pitts (2025) Strain-release trifluoromethoxylation and pentafluorosulfanoxylation of [1.1.0]bicyclobutanes: expanded access to fluorinated cyclobutane hybrid bioisosteres. Chemical communications (Cambridge, England). ISSN 1364-548X
Kranjc, Jaka, Tomašič, Tihomir, Pajk, Stane, Brinc, Matjaz, Pišlar, Anja and Anderluh, Marko (2025) New Inhibitors of β-1,4-Galactosyltransferase I Discovered by Virtual Screening. ChemMedChem, 20 (7). e202400896. ISSN 1860-7187
Kuroda, Yuki, Iida, Jun, Murata, Kozue, Hori, Yuki, Kobiki, Jumpei, Minatoya, Kenji and Masumoto, Hidetoshi (2025) Transplantation of vascularized cardiac microtissue derived from human iPS cells enhances the impaired electrical conduction capacity in a porcine model of myocardial injury. JTCVS Open. ISSN 26662736
L
Laouar, Nadia, Kramer, Mateja, Gallou, Fabrice, Chirino Chace, Bernardita, Jones, Graham and Duleba-Satz, Bozena (2025) Do networking and diversity elements impact the development of innovation leaders? A climate analysis in the pharmaceutical industry. Journal of Innovation Management, 12 (4). I-IX. ISSN 2183-0606
Lehermayr, Christian (2025) Current Industry Practices on Closed System Transfer Devices (CSTD) for Drug Products. Journal of pharmaceutical sciences. ISSN XPHS 3684
Lehmann, Hansjoerg, Ruppen, Thomas, Oswald, Susanne, Ye, Ning, Tian, Xiangguang, Dai, Chunhui and Fairhurst, Robin (2025) Development of a safe and efficient continuous flow method for the synthesis of 3-difluoromethoxypyridine derivatives. Helvetica chimica acta, 108 (e20240). ISSN 1522-2675
Li, Li, Lu, Yang-3 and Jia, Huang (2025) Optical and Electrical Dual-Mode Detection of a Carcinogenic Substance Based on Synergy of Liquid Crystals and Ionic Liquids. ACS Sensors. ISSN 2379-36942379-3694
Ling, Hui, Anderson, Lauren, Kubek-Luck, Katie, Burks, Tyler, Perner, Juliane, Schuierer, Sven, Ruda, Vera and Mansfield, Keith (2025) Single cell multi-omics reveals re-dosing with CD3 bispecific antibody induces a TCF7 high central memory CD8 + T cell population associated with reduced cytokine production. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 186. p. 117973. ISSN 1950-6007
Liu, Jing, Bluemel, Markus, Swisher, Jennifer, Jules, Felix, de Jong, Isabella, Litowski, Jennifer, Moses, Michael, Weiser, Sarah, Ibrahim, Basma, Clark, Nicholas and Hu, Qingyan (2025) Securing Patient Well-Being Best Practices for In-Use Stability and Compatibility Studies. BioProcess international., 23 (4). pp. 19-26.
Loberg, Lisa I., Proctor, William R., Burdick, Andrew D., Cauvin, Annick, DeLise, Anthony, Hemkens, Michelle, Hohlbaum, Andreas M., Hukkanen, Renee, Sdgwick, Alanna E., Shuey, Dana, Zane, Doris T. and Stamp, Katie (2025) Nonclinical teratogenicity safety assessment of CRBN-engaging targeted protein degraders: Points to consider. Regulatory toxicology and pharmacology : RTP. p. 105793. ISSN 1096-0295
Luteijn, Maartje, Mahboubi, Hicham, Trojer, Dominic, Handl, Cornelia, Pizzato, Nicolas, Pfeifer, Martin, Voshol, Johannes, Giorgetti, Elisa, Manneville, Carole, Garnier, Isabelle, Mueller, Matthias, Zeng, Fanning, Buntin, Kathrin, Markwalder, Roger, Schroeder, Harald, Weiler, Jan, Khar, Dora, Schuhmann, Tim, Groot Kormelink, Paul, Gubser Keller, Caroline, Farmer, Pierre, Mackay, Angela, Beibel, Martin, Roma, Guglielmo, D'Ario, Giovanni, Merkl, Claudia, Schebesta, Michael, Hild, Marc, Elwood, Fiona, Ripin, Nina, Chery, Antoine, Allain, Frederic, Labow, Mark, Gabriel, Daniela, Nash, Mark, Hunziker, Juerg and Meisner Kober, Nicole-Claudia (2025) Chemical manipulation of RNA foci mobilizes G4C2 repeat RNA from nuclear storage foci for translation into dipeptide repeat polyproteins in C9Orf72 ALS neurons. Nucleic acids research, 53 (7). pp. 1-28. ISSN 1362-4962; 0305-1048
M
Macy, Rebecca, Somanji, Flavio and Sverdlov, Alex (2025) Designing and developing a prescription digital therapeutic for at home heart rate variability biofeedback to support and enhance patient outcomes in post-traumatic stress disorder treatment. Frontiers in Digital Health, 7. ISSN 2673-253X
Maertins, Katja (2025) JAS Case Studies:Weight of Evidence Approach with Different Feedback from Health Authorities. JAS Case Studies:�Weight of Evidence Approach with Different Feedback from Health Authorities.
Millar, Neal L, McInnes, Ian B, Kolbinger, Frank, Raulf, Friedrich, Akbar, Moeed, Li, Yufei, Beckmann, Nicolau, Accart Gris, Nathalie, Leupin, Olivier, Calonder, Claudio, Schieker, Matthias, Kneissel, Michaela, Bruns, Christian, Siegel, Richard and Weber, Eckhard (2025) Targeting the IL-17A pathway for therapy in early-stage tendinopathy. Rheumatic & musculoskeletal diseases open., 11 (1). e004729. ISSN 2056-5933
N
Naiel, S., Dowdall, N., Zhou, Q., Ali, P., Hayat, A., Vierhout, M., Wong, E.Y., Couto, R., Yépez, B., Seifried, B., Moquin, P., Kolb, M.R., Ask, K. and Hoare, T. (2025) Modulating pro-fibrotic macrophages using yeast beta-glucan microparticles prepared by Pressurized Gas eXpanded liquid (PGX) Technology®. Biomaterials, 313. p. 122816. ISSN 01429612
P
Panikulam, Sherin, Morgan, Hannah, Gutknecht, Michael, Karle, Anette, Rajaratnam, Atchaya, Muntwyler, Jennifer, Anderka, Oliver, Lebesgue, Nicolas and Villiger, Thomas (2025) Assessing the adjuvant potential of CHO host cell proteins using an in vitro dendritic cell assay. Biotechnology and Bioengineering. ISSN 0006-35921097-0290
Panikulam, Sherin, Morgan, Hannah, Gutknecht, Michael, Villiger, Thomas K., Lebesgue, Nicolas and Karle, Anette (2025) Host cell protein-mediated adjuvanticity and immunogenicity risks of biotherapeutics. Biotechnology advances., 81. ISSN https://doi.org/10.1016/j.biotechadv.2025.108575
Pecaric Strnad, Urska, Osterman, Natan, Zalokar, Petra and Zidar, Mitja (2025) Small scale model for predicting transportation-induced particle formation in biotherapeutics. Colloids and surfaces, series B : biointerfaces, 245. p. 114304. ISSN 09277765
Pfeifer, Martin, Reinhardt, Juergen, Chang, Lena, Kohlbrenner, Mariah, Goldmann, Ulrich, Garofoli, Andrea, Sedlyarov, Vitaly, Bichler, Manuel, Wolf, Gernot, Christodoulaki, Eirini, Ingles-Prieto, Alvaro, Ferrada, Evandro, Frommelt, Fabian, Thing Teoh, Shao, Leippe, Philipp, Haladik, Ben, Selzer, Paul, Digles, Daniela, Ecker, Gerhard, Osthushenrich, Tanja, McNamara, Aidan, Hepworth, David, Wiedmer, Tabea and Superti-Furga, Giulio (2025) Data- and knowledge-derived functional landscape of human solute carriers. Molecular systems biology. pp. 1-33. ISSN 1744-4292
Plasschaert, Lindsey W, Stutz, Cian, Otarola, Ester, Shang, Jianyu, Valdez Misiolek, Rachel, Choo-Wing, Rayman, Quigley, Catherine, Ruggeri, Lionello, Taddese, Bruck, Decock, Arnaud, Nuccio, Arthur, Watson, Rebecca, Kubek-Luck, Katie, Ibrahim Aibo, Daher, Magnifico, Maria, Buchs, Mirjam, Tan, Ge, Lin, Amy-1, Ashley, Louise, Wang, Hsu-Kun, Bardroff, Michael and Wetzel, Kristie (2025) A systemically delivered AAV-CFTR gene therapy approach for cystic fibrosis. A systemically delivered AAV-CFTR gene therapy approach for cystic fibrosis. ISSN 2692-8205
Prasnikar, Monika, Bjelosevic Ziberna, Maja, Krzisnik, Nika, Roskar, Robert, Grabnar, Iztok, Ahlin Grabnar, Pegi and Zula, Ales (2025) Additive effects of the new viscosity-reducing and stabilizing excipients for monoclonal antibody formulation. International journal of pharmaceutics, 674. p. 125451. ISSN 1873-3476
R
Radhouani, Mariem, Farhat, Asma, Hakobyan, Anna, Zahalka, Sophie, Pimenov, Lisabeth, Fokina, Alina, Hladik, Anastasiya, Lakovits, Karin, Zech, Andreas, Idzko, Marko, Krausgruber, Thomas, Uluckan, Ozge, Kovarik, Jiri, Hoehlig, Kai, Vater, Axel, Menche, Joerg, Knapp, Sylvia and Starkl, Philipp (2025) Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation. Science immunology, 10 (106). eadp6231. ISSN 2470-9468
Ragucci, Erasmo, Uboldi, Marco, Sobczuk, Adam Antoni, Facchetti, Giorgio, Melocchi, Alice, Serratoni, Mauro and Zema, Lucia (2025) Feasibility of Hot Melt Extrusion in Converting Water-Based Nanosuspensions into Solid Dosage Forms. Pharmaceutics, 17 (5). p. 662.
Ratuski, Anna S, Thiel, Jacob H., Ahloy-Dallaire, Jamie, Gaskill, Brianna, Pritchett-Corning, Kathleen R., Felt, Stephen A. and Garner, Joseph P (2025) Risk factors for barbering in laboratory mice. Scientific reports, 15 (1). p. 7456. ISSN 2045-2322
Reilly, John, Welch, Christopher, Lozacâ��h, Marie-Anne, Meishammer, Aldo, Reck, Marcel, Fairhurst, Robin and McKenna, Jeffrey-1 (2025) A ‘One-Shot’ Strategy for Preparative Chiral SFC with Chiroptical Detection Accelerates Purification and Enhances Characterization for Drug Discovery. Journal of Chromatography A, 1744 (15). pp. 1-8. ISSN 465720
Ritzmann, Ramona, Paul, Jochen, Gasser, Juerg A, Kuch, Janine, Li, YUFEI, Honorio, Ines, Beretta-Picoli, Agnese, Doelemeyer, Arno, Meyer, Angelika, Hils, Lukas, Utzinger, Stephan, Heitner, Albrecht, Jacobi, Carsten and Centner, Christoph (2025) In vivo biomechanical correlates of gait and stair climbing are predictors of ex vivo cartilage quality in gonarthrotic patients. Journal of biomechanics.
S
Schiantarelli, Julia, Benamar, Mouadh, Park, Jihye, Hodi, Stephen F., Johnson, Douglas B., Bosma-Moody, Alice, Liu, David, Campbell, Katie, Ribas, Antoni, Van Allen, Eliezer and Haq, Rizwan (2025) Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma. Cancer cell, 43 (2). 308-316.e6. ISSN 1878-3686
Shen, Dong-Ming, Byth, Kate F, Bertheloot, Damien, Braams, Simona, Bradley, Sarah, Dean, Dennis, Dekker, Carien, El-Kattan, Ayman F, Franchi, Luigi, Glick, Gary D, Ghosh, Shomir, Hinniger, Alexandra, Katz, Jason, Kitanovic, Ana, Lu, Xiaokang, Olhava, Edward J, Opipari, Anthony W, Sanchez, Brian, Seidel, H. Martin, Stunden, James, Stutz, Andrea, Telling, Alissa, Venkatraman, Shankar, Winkler, David G and Roush, William R (2025) Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor. Journal of medicinal chemistry. ISSN 1520-4804
T
Thoma, Gebhard, Orain, David, Spanka, Carsten, Decoret, Odile, Hurley, Brian, Cheung, Atwood, Sandham, David, Honda, Ayako, Tichkule, Ritesh, Chen, Xin2, Patel, Tajesh, Labbe-Giguere, Nancy, Tan, Kian, Manchester, John, Srinivas, Honnappa, Penno, Carlos, Numao, Shin, Schopfer, Ulrich, Jaeger, Petra-1, Wack, Nathalie, Hasler, Franziska, Sindelar, Miriam, Loetscher, Pius, Kiffe, Michael, Ren, Xiaojun, Subramanian, Khaushik, Growcott, Ellie and Roehn, Till (2025) Discovery of GJG057, a Potent and Highly Selective Inhibitor of Leukotriene C4 Synthase. Journal of medicinal chemistry, 68. pp. 4721-4742.
Tian, Yingtao, Lanz, Marian, Hoehn, Pascale, Wang, Xiangshan, Wiss, Jacques, Heuberger, Christoph, Jean-Luc, Schmuck, Jiang, Xigui-1, Wang, Jingen and Ding, Yiping (2025) Application-based calibration method for calorimeter FlexyTSC SEDEX. Journal of Thermal Analysis and Calorimetry.
Tourdot, Sophie, Bloem, Karin, Champion, Lysie, de Groot, Anne, Ducret, Axel, Fraser, Sasha, Garide, Patrick, Grudzinska-Goebel, Joanna, Gutknecht, Michael, Hickling, Timothy, Horling, Frank, Ichetovkin, Marina, Johnson, Alison, Jyamubandi, Issa, Karle, Anette, Kromminga, Arno, Kurtulmus, Ebru Aydin, Loeff, Floris, Maillere, Bernard, Michaut, Lydia, Minelli, Francesca, Nielsen, Morten, Nayak, Vivek, Nelson, Robert, Pallardy, Marc, Pattyn, Sofie, Pedras-Vasconelos, Joao, Pepermans, Elise, Poyau, Alain, Reichel, Matthias, Rosenberg, Amy, Sauna, Zuben, Saxena, Manisha, Smith, Noel, Snoeck, Veerle, Thoo, Lester, Tovey, Michael, Verthelyi, Daniela, Wuttke, Rene, Yerly, Daniel and Kramer, Daniel (2025) Proceedings of the 15th European Immunogenicity Platform Open Symposium on Immunogenicity of Biopharmaceuticals. to be determined, 17 (1). ISSN https://doi.org/10.1080/19420862.2025.2487604
Tourdot, Sophie, Bloem, Karin, Champion, Lysie, de Groot, Anne, Ducret, Axel, Fraser, Sasha, Garide, Patrick, Grudzinska-Goebel, Joanna, Gutknecht, Michael, Hickling, Timothy, Horling, Frank, Ichetovkin, Marina, Johnson, Alison, Jyamubandi, Issa, Karle, Anette, Kromminga, Arno, Kurtulmus, Ebru Aydin, Loeff, Floris, Maillere, Bernard, Michaut, Lydia, Minelli, Francesca, Nielsen, Morten, Nayak, Vivek, Nelson, Robert, Pallardy, Marc, Pattyn, Sofie, Pedras-Vasconelos, Joao, Pepermans, Elise, Poyau, Alain, Reichel, Matthias, Rosenberg, Amy, Sauna, Zuben, Saxena, Manisha, Smith, Noel, Snoeck, Veerle, Thoo, Lester, Tovey, Michael, Verthelyi, Daniela, Wuttke, Rene, Yerly, Daniel and Kramer, Daniel (2025) Proceedings of the 15th European Immunogenicity Platform Open Symposium on Immunogenicity of Biopharmaceuticals. mAbs, 16 (1). ISSN https://doi.org/10.1080/19420862.2024.2324801
U
Udovic, Erika (2025) Comprehensive extractables and leachables sensitization analysis and practical application of a risk-based approach to sensitization assessment for parenteral drug products. Regulatory toxicology and pharmacology : RTP, 157 (105776). ISSN 1096-0295
V
Vazvaei-Smith, Faye, Li, Wenkui, Barnaby, Omar, Bhardwaj, Sanjeev, Dong, Juyao, Dumont, Carolyne, Fernandez-Metzler, Carmen, Geist, Brian, Hassanein, Mohamed, Hays, Amanda, Ilinskaya, Anna, Kadar, Eugene, King, Kris, Kulagina, Nadia, Matta, Murali, Midde, Krishna, Pan, Rina, Pathania, Divya, Tarnowski, Thomas, Tewalt, Eric, Thomas, Eric, Wickremsinhe, Enaksha and Xiao, Deqing (2025) Best Practices and Recommendations for Non-Liquid Matrices Bioanalysis. AAPS J.
Velcicky, Juraj, Cremosnik, Gregor, Scheufler, Clemens, Meier, Peter, Wirth, Emmanuelle, Felber, Richard, Ramage, Paul, Schaefer, Michael, Kaiser, Christian, Lehmann, Sylvie, Kutil, Raphaela, Singeisen, Sandra, Mueller-Ristig, Dorothee, Popp, Simone, Cebe, Regis, Lehr, Philipp, Kaupmann, Klemens, Erbel, Paulus, Roehn, Till, Giovannoni, Jerome, Dumelin, Christoph and Martiny-Baron, Georg (2025) Discovery of Selective Low Molecular Weight Interleukin-36 Receptor Antagonists by Encoded Library Technologies. Nature communications, 16. p. 1669. ISSN 2041-1723
Velcicky, Juraj, Ngo, Estelle, Bauer, Matthias-1, Meyer, Arndt, Schlapbach, Achim, Racine, Sophie, Orain, David, Pflieger, Daniel, Teixeira-Fouchard, Sylvie, Dubois, Celine, Goetz, Alban-1, Steiner, Roland, Palmieri, Marco, Bussenault, Alex, Stringer, Rowan, Larger, Patrice, Riek, Simone, Schmutz, Patrick, Sylvie, Lehmann, Scheufler, Clemens, Jean-Michel, Rondeau, Burkhart, Christoph, Knoepfel, Thomas and Gommermann, Nina (2025) Thiazole-Based IL-17 Inhibitors Discovered by Scaffold Morphing. ChemMedChem : chemistry enabling drug discovery, 20. e202400851. ISSN 1860-7187; 1860-7179
Vicart, Axel, Holland, Cam, Fraser, Kathryn, Gervais, Frederic, Aspinall-O'Dea, Mark, Brown, Nick, Siddals, Kirk, Greiner, Geraldine, Carreira, Vinicius, Galbreath, Elizabeth, Willer, Maggie, Kaliyaperumal, Saravanan, Wood, Charles, MacLachlan, Timothy and Clark, Elizabeth (2025) Applications of Cell-Based Protein Array Technology to Preclinical Safety Assessment of Biological Products. Toxicologic pathology. p. 1926233241311259. ISSN 1533-1601
W
Wang, Yan, Son, Long, Fernandes, Luciana, Wang, Yu-Hsiu, Zou, Jing, Franklin, Samuel, Hu, Yanping, Palmer, Lee, Yeung, Jason, Barriga, Daniela, Russel, William, Moquin, Stephanie, Shi, Pei-Yong, Skepper, Colin and Xie, Xuping (2025) Mechanistic insights into dengue virus inhibition by a clinical trial compound NITD-688. Proceedings of the National Academy of Sciences of the United States of America, 122 (13). e2426922122. ISSN 1091-6490
Wojcik, John, Sikorski, Tim, Huang, Yue, Wang, Jian, Sugimoto, Hiroshi, Baratta, Mike, Ciccimaro, Eugene, Green, Rachel, Jian, Wenying, Yeoun, Jin Kim, Lassman, Michael, Mohapatra, Suvovan, Qian, Mark, Kar, Sumit, Rosenbaum, Anton, Sarvaiya, Hetal, Tian, Yu, Cainshtein, Inna, Yuan, Long, Tao, Lin, Ji, Allena, Kochansky, Chris, Qiu, Haibo, Maes, Estelle, Chen, Linzhi, Cooley, Megan, Dufield, Dawn, Hyer, Elizabeth, Johnson, Jay, Li, Wenkui, Liu, Aihua, Lu, Yang, Meissen, John, Palandra, Joe, Tang, Xiaonan, Vigil, Adam, Wei, Wei, Vinter, Stephen, Xue, Yongjun, Yang, Li, Zheng, Naiyu, Benson, Kim, McCush, Fred, Liang, Zhenmin, Abberley, Lee, Andisik, Matt, Araya, Marcela, Cho, Julia, Colligan, Liliana, Dasgupta, Arindam, Dudek, Markus, Edmison, Anna, Fischer, Sally, Folian, Brian, Garofolo, Fabio, Ishii-watabe, Akiko, Ivanova, Dany, Kwadijk-De Gijsel, Sonja, Luo, Lina, McGuinness, Michael, O'Day, Christine, Salehzadeh-Asi, Reza, Neto, Joao, Verhaeghe, Tom, Wan, Katty, Whale, Emma, Yan, Weili, Yang, Eric and Zhang, Jinhui (2025) 2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management; ELN Migration; Ultra-Sensitivity Mass Spectrometry (Part 1A - Recommendations on Advanced Strategies for Mass Spectrometry Assays, Chromatography, Sample Preparation and BMV/Regulated Bioanalysis Part 1B - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV). Bioanalysis. pp. 1-39. ISSN 1757-6199
Wu, Bin-3, Huang, Jianxun, Pei, Chao, Yang, He and Tang, Wenjun (2025) Enantioselective Palladium-Catalyzed α-Arylation of Acyclic Esters. Angewandte Chemie (International ed. in English). e202505458. ISSN 1521-3773
Wu, Ellen-1, Macklin, Sarah, Zhang, Yanling, Thai, Kerri, Nghiem, Linda, Di Ciano‐Oliveira, Caterina, Coelho, Nuno, Wang, Hai, Advani, Suzanne L., Desjardins, Jean‐François, Yuen, Darren A, Misra, Paraish, Connelly, Kim A., Nyengaard, Jens R. and Gilbert, Richard E. (2025) Induction of proximal tubular proliferation and lengthening in response to sodium glucose linked cotransporter‐2 inhibition in experimental rats. Journal of Diabetes Investigation. ISSN 2040-1116
Wu, Tianrui, Castro, Anthony, Ganguli, Kasturi, Ye, Ning, Gallou, Fabrice, Wu, Bin-3 and Weix, Daniel (2025) Cross-Electrophile Coupling to form Sterically Hindered C(sp2)-C(sp3) Bonds: Ni and Co Afford Complementary Reactivity. Journal of the American Chemical Society JACS..
X
Xiang, Chuanxi, Raghunathan, Vijay, Qiu, Yubin, Mehta, Manisha, Demirs, John, Grosskreutz, Cyndy, Wilson, Chris and Prasanna, Ganesh (2025) Multiparametric grading of glaucoma severity by histopathology can enable post-mortem substratification of disease state. Acta neuropathologica communications., 13 (1). p. 3. ISSN 2051-5960