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Article

Aguiar, Carla J, Rocha-Franco, Joao A, Souza, Pedro A, Santos, Anderson K, Ladeira, Marina, Rocha-Resende, Cibele, Ladeira, Luis O, Resende, Rodrigo R, Botoni, Fernando A, Barrouin Melo, Marcos, Lima, Cristiano X, Carballido, Jose, Cunha, Thiago M, Menezes, Gustavo B, Guatimosim, Silvia and Leite, M Fatima (2014) SUCCINATE CAUSES CARDIOMYOCYTE HYPERTROPHY THROUGH GPR91 ACTIVATION. Cell Communication and Signaling.

Ahene, A, Calonder, C, Davis, S, Kowalchick, J, Nakamura, T, Nouri, P, Vostiar, I, Wang, Y and Wang, J (2014) Automation practices in large molecule bioanalysis: Recommendations from group l5 of the global bioanalytical consortium. AAPS journal. pp. 164-171.

Akkus, Funda, Terbeck, Sylvia, Ametamey, Simon/M, Rufer, Michael, Treyer, Valerie, Burger, Cyrill, Johayem, Annas, Gomez-Mancilla, Baltazar, Sovago, Judit, Buck, Alfred and Hasler, Gregor (2014) Metabotropic Glutamate Receptor 5 Binding in Patients with Obsessive-Compulsive Disorder. International Journal of Neuropsychopharmacology.

Alper, Phillip and Epple, Robert (2014) Discovery of structurally novel, potent and orally efficacious GPR119 agonists. Bioorganic and Medicinal Chemistry Letters, 24 (10). pp. 2383-2387. ISSN 1464-3405

Amato, Anthony A, Sivakumar, Kumaraswamy, Goyal, Namita, David, William S, Salajegheh, Mohammad, Praestgaard, Jens, Trifilieff, Estelle, Trendelenburg, Anne-Ulrike, Laurent, Didier, Glass, David, Roubenoff, Ronenn, Tseng, Brian and Greenberg, Steven A (2014) Treatment of sporadic inclusion body myositis with bimagrumab. Neurology, 83 (24). pp. 2239-2246. ISSN 1526-632X

Ando, Yuichi, Inada-inoue, Megumi, Mitsuma, Ayako, Yoshino, Takayuki, Ohtsu, Atsushi, Noumi, Naoko, Sato, Masahiko, Kakizume, Tomoyuki, Robson, Matthew, Quadt, Cornelia and Doi, Toshihiko (2014) A Phase I dose-escalation study of buparlisib (BKM120), an oral pan-class I PI3K inhibitor, in Japanese patients with advanced solid tumors. Cancer Science, 105 (3). pp. 347-353.

Antczak, Christophe, Somalinga, Balajee and Djaballah, Hakim (2014) Heat shock proteins: A high content assay opportunity to measure cellular stress response. European Drug Target Review.

Arias, Hugo R, Feuerbach, Dominik, Targowska-Duda, Katarzyna M, Kaczor, Agnieszka A, Poso, Antti and Jozwiak, Krzysztof (2014) Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human 42 and 34 subtypes. Biochimica et Biophysica Acta.

Arm, Jonathan, Bottoli, Ivan, Skerjanec, Andrej, Groenewegen, Andrea, Maahs, Suzanne, Owen, Charles, Jones, Ieuan and Lowe, Phil (2014) Efficacy and safety of QGE031, a novel anti-IgE antibody, in atopic subjects. Clinical and Experimental Allergy, 44 (11). pp. 1371-1385.

Arnold, Nicola, Beattie, David, Bradley, Michelle, Brearley, Andrew, Brown, Lyndon, Charlton, Steven, Farr, David Colin, Fozard, John R., Fullerton, Joe, Gosling, Martin, Hatto, Julia, Janus, Diana, Jones, Darryl, Jordan, Lynne, Lewis, Christine, Maas, Janet, Mercer, Mark, Oakman, Helen, Press, Neil, Profit, Rachael, Schuerch, Friedrich, Sykes, David, Taylor, Roger, Trifilieff, Alexandre, Tuffnell, Andrew and Mccarthy, Clive (2014) The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting beta2-adrenoceptor agonist. Bioorganic and Medicinal Chemistry Letters, 24. pp. 4341-4347.

Aronchik, Ida, Appleton, Brent, Basham, Stephen, Crawford, Kenneth, Del Rosario, Merci, Doyle, Laura, Estacio, William, Lindvall, Mika, Luu, Catherine, Venetsanakos, Eleni, Shafer, Cynthia and Jefferson, A.B. (2014) Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers. Molecular Cancer Research, 12 (5). pp. 803-812. ISSN 1557-3125

Aronchik, Ida, Appleton, Brent, Basham, Stephen, Crawford, Kenneth, Del Rosario, Merci, Doyle, Laura, Estacio, William, Lindvall, Mika, Luu, Catherine, Venetsanakos, Eleni, Shafer, Cynthia and Jefferson, A.B. (2014) Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers. Molecular Cancer Research, 12 (5). pp. 803-812. ISSN 1557-3125

Auberson, Yves, Troxler, Thomas J., Zhang, Xuechun, Yang, Charles, Fendt, Markus, Feuerbach, Dominik, Liu, Yu-Chih, Lagu, Bharat, Lerchner, Andreas, Perrone, Mark, Lei, Lijun, Zhang, Chao, Wang, Chunxiu, Wang, Tie-Lin and Bock, Mark (2014) Ergoline-derived Inverse Agonists of the Human H3-Receptor for the Treatment of Narcolepsy. ChemMedChem. ISSN 18607179

Auberson, Yves, Troxler, Thomas J., Zhang, Xuechun, Yang, Charles, Feuerbach, Dominik, Liu, Yu-Chih, Lagu, Bharat, Perrone, Mark, Lei, Lijun, Shen, Xiaoxia, Zhang, Dushan, Wang, Chunxiu, Wang, Tie-Lin and Bock, Mark (2014) From Ergolines to Indoles: Improved Inhibitors of the Human H3-Receptor for the Treatment of Narcolepsy. ChemMedChem, 10 (2). pp. 266-275. ISSN 18607179

Auld, Douglas (2014) October Literature Search and Review. Assay and Drug Development Technologies. ASSAY and Drug Development Technologies.

Auld, Douglas (2014) September Literature Search and Review. Assay and Drug Development Technologies. Assays and Drug Development Technologies.

Auld, Douglas, Hill, William and Orme, Jonathon (2014) Examining Ligand-based Stabilization of Proteins in Cells with MEK1 Kinase Inhibitors. Assay Drug Development Technologies, 13 (5). pp. 266-276. ISSN 1540-658X1557-8127

Auld, Douglas, Hill, William, Smith, Thomas, Zhang, Ji, Kang, Zhao Bin, Ho, Pei-I, Ardayfio, Ophelia and Bowes, Scott (2014) Applications of quantitative HTS (qHTS) to facilitate assay pilot testing. Journal of Biomolecular Screening, 19 (5). pp. 651-660. ISSN 1087-05711552-454X

Austin, Steven, Dunstan, David, Reilly, John, Wall, Daniel, Ek, Jared and Mckinnon, Michael (2014) The Implementation of Spotfire to Analyze Open-Access Instrumentation Metrics. Chromatography Today, Aug-Se. pp. 2-4.

Avchalumov, Yosef, Sander, Svenja, Porath, Katrin, Hamann, Melanie, Richter, Franziska, Kirschstein, Timo, Köhling, Rüdiger and Richter, Angelika (2014) Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia. Experimental Neurology, 261. pp. 677-684. ISSN 00144886

Azimioara, Mihai, Epple, Robert, Alper, Phillip, Cow, Christopher, Mutnick, Daniel, Nikulin, Victor, Lelais, Gerald, Mcneill, Matthew, Michellys, Pierre, Wang, Zhiliang, Li, Jing, Bao, Dingjiu, Zoll, Jocelyn, Kim, Young, Zimmerman, Matthew, Groessl, Todd, Tuntland, Tove, Mcnamara, Peter, Seidel, Martin, Joseph, Sean, Mecom, John, Reding, Esther and Paliotti, Michael (2014) Novel tricyclic pyrazolopyrimidines as potent and selective GPR119 agonists. Bioorganic and Medicinal Chemistry Letters, 24 (23). pp. 5478-5483. ISSN 1464-3405

Bachelier, Richard, Confavreux, Cyrille, Goehring, Delphine, van der Pluijm, Gabri, Clezardin, Philippe and Carmeli, Yael (2014) Combination of Antiangiogenic Therapies Reduces Osteolysis and Tumor Burden in Experimental Breast Cancer Bone Metastasis. International journal of cancer, 135 (6). pp. 1319-1329. ISSN 1097-0215

Baertschi, Stefan, Baur, Nina, Lueders-Lefevre, Valerie, Voshol, Johannes and Keller, Hansjoerg (2014) Class I and IIa Histone Deacetylases Have Opposite Effects on Sclerostin Gene Regulation. Journal of Biological Chemistry.

Barnes, David, Boiselle, Carri, Chopra, Rajiv, Hoffmaster, Keith, Kato, Mitsunori, Lin, Kai, Pan, Guoyu, Zheng, Rui, Shu, Lei, Ma, Sue, Wang, Jianling, Whiteman, Leah, Xu, Mei and Fu, Jiping (2014) Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors. Bioorganic & Medicinal Chemistry Letters, 24 (16). pp. 3979-3985. ISSN 0960894X

Barone, Eugenio, Mosser, Sebastien and Frearing, Patrick C (2014) Cofilin-1 activity is modulated by age, Alzheimer's disease pathology and gamma secretase. Biochim Biophys Acta, 1842 (12 Pt ). pp. 2500-2509.

Baskin, KK, Rodriguez, MR, Kansara, S, Chen, W, Carranza, S, Frazier, OH, Glass, DJ and Taegtmeyer, H (2014) MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart. Journal of Molecular and Cellular Cardiology. pp. 168-176.

Bassilana, Frederic, Carlson, Adam, Dasilva, Jennifer, Grosshans, Bianka, Vidal, Solange, Beck, Valerie, Wilmering Wetter, Barbara, Llamas, Luis, Bourret, Aaron, Wu, Xu, Harbinski, Fred, Ruffner, Heinz, Grandi, Paola, Schirle, Markus, Jenkins, Jeremy, Bouwmeester, Antonius, Porter, Jeffrey, Myer, Vic, Finan, Peter, Tallarico, John, Kelleher Iii, Joseph, Seuwen, Klaus, Jain, Rishi and Luchansky, Sarah (2014) Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39. Nature Chemical Biology, 10 (5). pp. 343-349. ISSN 1552-4469

Bauer, Daniel, Averett, Lacey A, De Smedt, Ann, Kleinman, Mark H, Muster, Wolfgang, Pettersen, Betty A and Robles, Catherine (2014) Standardized UV-vis spectra as the foundation for a threshold-based, integrated photosafety evaluation. Regulatory Toxicology and Pharmacology, 68 (1). pp. 70-75. ISSN 02732300

Beale, J, Jayaraman, A, Jackson, DJ, Macintyre, JD, Edwards, MR, Walton, RP, Zhu, J, Ching, YM, Shamji, B, Edwards, M, Westwick, J, Cousins, DJ, Hwang, YY, McKenzie, A, Johnston, SL and Bartlett, NW (2014) Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation. Science Translational Medicine. 256ra134-.

Beck, Jeremy and Springer, Clayton (2014) Quantitative structure-activity relationship models of chemical transformations from matched pairs analyses. Journal of chemical information and modeling, 54 (4). pp. 1226-1234. ISSN 1549-960X

Becker, Dieter, Zhang, Jin, Heimbach, Tycho, Kulmatycki, Kenneth, Shimizu, Jeff, Dole, Kiran, He, Handan and Wanke, Christoph (2014) Novel orally swallowable IntelliCap(®) device to quantify regional drug absorption in human GI tract using diltiazem as model drug. AAPS PharmSciTech, 15 (6). pp. 1490-1497. ISSN 1530-9932

Bell, RE, Khaled, M, Netanely, D, Schubert, S, Golan, T, Buxbaum, A, Janas, MM, Postolsky, B, Goldberg, MS, Shamir, R and Levy, C (2014) Transcription factor/microRNA axis blocks melanoma invasion program by miR-211 targeting NUAK1. Journal of Investigative Dermatology. pp. 441-451.

Berghausen, Joerg and Faller, Bernard (2014) Diagnosing solubility limitations – the example of hydrate formation (revised). ADMET & DMPK.

Bernat, Viachaslau, Brox, Regine, Heinrich, Markus, Auberson, Yves and Tschammer, Nuska (2014) Ligand biased and probe-dependent modulation of the chemokine receptor CXCR3 signaling by negative allosteric modulators. ChemMedChem, 10 (3). pp. 566-574. ISSN 18607179

Bhinder, B, Antczak, C, Shum, D, Radu, C, Mahida, JP, Liu-Sullivan, N, Ibanez, G, Raja, BS, Calder, PA and Djaballah, H (2014) Chemical & RNAi screening at MSKCC: A collaborative platform to discover & repurpose drugs to fight disease. Combinatorial Chemistry and High Throughput Screening. pp. 298-318.

Bhinder, Bhavneet, Antczak, Christophe, Shum, David, Radu, Constantin, Mahida, Jeni, Liu-Sullivan, Nancy, Ibanez, Glorymar, Somalinga Raja, Balajee, Calder, Paul and Djaballah, Hakim (2014) Chemical & RNAi Screening at MSKCC: A Collaborative Platform to Discover & Repurpose Drugs to Fight Disease. Combinatorial Chemistry & High Throughput Screening, 17 (4). pp. 298-318. ISSN 1875-5402

Bialek, P, Parkington, J, Li, X, Gavin, D, Wallace, C, Zhang, J, Root, A, Yan, G, Warner, L, Seeherman, HJ and Yaworsky, PJ (2014) A myostatin and activin decoy receptor enhances bone formation in mice. Bone. pp. 162-171.

Bigaud, Marc, Guerini, Danilo, Billich, Andreas, Bassilana, Frederic and Brinkmann, Volker (2014) Second generation S1P receptor modulators: Research strategies and clinical developments. Biochimica et Biophysica Acta - Molecular and cell Biology of lipids, 1841 (5). pp. 754-758. ISSN 1388-1981

Bill, A, Popa, MO, van Diepen, MT, Gutierrez, A, Lilley, S, Velkova, M, Acheson, K, Choudhury, H, Renaud, NA, Auld, DS, Gosling, M, Groot-Kormelink, PJ and Gaither, LA (2014) Variomics screen identifies the reentrant loop of the calcium-activated chloride channel ANO1 that facilitates channel activation. Journal of Biological Chemistry .

Bin, Huang, Tanja, Lucas, Claudia, Küppers, Xiaomin, Dong, Maike, Krause, Alexander, Bepperling, Johannes, Buchner, Voshol, Johannes, Andreas, Weiss, Gerrits, Bertran and Stefan, Kochanek (2014) Scalable production of full-length normal and mutant huntingtin in human cells and its biochemical characterization. PLOS ONE.

Blackford, J, Brimacombe, KR, Dougherty, EJ, Pradhan, M, Shen, M, Li, Z, Auld, DS, Chow, CC, Austin, CP and Stoney, S (2014) Research resource: Modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay. Molecular Endocrinology. pp. 1194-1206.

Blasco, Francesca, Fu, Yilong, Chen, Yen Liang, Herve, Maxime Marcel, Gu, Feng and Shi, Pei-Yong (2014) Development of a FACS-based assay for evaluating antiviral potency of compound in dengue infected peripheral blood mononuclear cells. Journal of Virological Methods, 196. pp. 18-24. ISSN 1879-0984

Boettcher, Andreas, Gradoux, Nathalie, Lorthiois, Edwige, Brandl, Trixi, Orain, David, Schiering, Nikolaus, Cumin, Frederic, Woelcke, Julian and Hassiepen, Ulrich (2014) Fluorescence Lifetime-based Competitive Binding Assays for Measuring the Binding Potency of Protease Inhibitors In Vitro. Journal of Biochemical Screening, 19 (6). pp. 870-877. ISSN 1087-05711552-454X

Bonapace, Laura, coissieux, marie-may, wyckoff, jeffrey, Mertz, Kirsten D., Varga, Zsuzsanna, Junt, Tobias and Bentires-Alj, Mohamed (2014) Discontinuation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature, 515 (7525). pp. 130-133.

Bonapace, Laura, wyckoff, Jeffrey, Mertz, Kirsten D., Varga, Zsuzsanna, coissieux, marie-may, Junt, Tobias and Bentires-Alj, Mohamed (2014) Cessation of CCL2 Inhibition Precipitates Breast Cancer Metastases and Death. Nature.

Bots, M, Verbrugge, I, Martin, BP, Salmon, JM, Ghisi, M, Baker, A, Stanley, K, Shortt, J, Ossenkoppele, GJ, Zuber, J, Rappaport, AR, Atadja, P, Lowe, SW and Johnstone, RW (2014) Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood. pp. 1341-1352.

Boudon, Stephanie Marie, Morandi, Gregory, Prideaux, Brendan , Staab, Dieter, Junker Walker, Ursula, Odermatt, Alex, Stoeckli, Markus and Bauer, Daniel (2014) EVALUATION OF SPARFLOXACIN PHOTOTOXICITY USING MASS SPECTROMETRY IMAGING. Journal of the American Society for Mass Spectrometry, 25 (10). pp. 1803-1809. ISSN 1879-1123

Boudon, Stephanie Marie, Plappert Helbig, Ulla, Odermatt, Alex and Bauer, Daniel (2014) CHARACTERIZATION OF VEMURAFENIB PHOTOTOXICITY IN A MOUSE MODEL. Toxicological Sciences, 137 (1). pp. 259-267. ISSN 1096-60801096-0929

Boudreaux, Ramon D , Perticone, Jacqueline I , Ellman, Rachel , Lenfest, Scott E , Bloomfield, Susan A and Hogan, Harry A (2014) Sequential High-Impact Loading and Zoledronic Acid Before Hindlimb Unloading Protects Against Decrements in Bone Microarchitecture and Strength. Published Thesis: http://oaktrust.library.tamu.edu/handle/1969.1/152600.

Bourgailh, Julien, Garnier, Maxime, Nufer, Robert, Pirard, Hans, Walles, Markus and Swart, Pieter Jacob (2014) ViewLux Microplate Imager for Metabolite Profiling: Validation and Applications in Drug Development. J Anal Bioanal Tech.

Boutouyrie-Dumont, B (2014) How to link biomarkers using physiologically based pharmacokinetic models. Biomarkers in Medicine. p. 74.

Boutouyrie-Dumont, B (2014) An IL-17-mediated paracrine network promotes tumor resistance to antiangiogenic therapy. Biomarkers in Medicine. p. 73.

Boutouyrie-Dumont, B (2014) A new biomarker to identify high-risk renal transplant patients. Biomarkers in Medicine. p. 75.

Boutouyrie-Dumont, Bruno (2014) How to link biomarkers using physiologically based pharmacokinetic models. Biomarkers in Medicine, 8 (1). pp. 73-75. ISSN 1752-0363

Boutouyrie-Dumont, Bruno (2014) An IL-17-mediated paracrine network promotes tumor resistance to antiangiogenic therapy. Biomarkers in Medicine, 8 (1). pp. 73-75. ISSN 1752-0363

Boutouyrie-Dumont, Bruno (2014) A new biomarker to identify high-risk renal transplant patients. Biomarkers in Medicine, 8 (1). pp. 73-75. ISSN 1752-0363

Boyce, SE, Tirunagari, N, Niedziela-Majka, A, Perry, J, Wong, M, Kan, E, Lagpacan, L, Barauskas, O, Hung, M, Fenaux, M, Appleby, T, Watkins, WJ, Schmitz, U and Sakowicz, R (2014) Structural and regulatory elements of HCV NS5B polymerase - beta-loop and C-terminal tail - Are required for activity of allosteric thumb site II inhibitors. PLoS ONE.

Breitschaft, A, Hu, K, Darstein, C, Ligueros-Saylan, M, Jordaan, P, Song, D, Hudson, M and Shah, R (2014) Effects of Subcutaneous Pasireotide on Cardiac Repolarization in Healthy Volunteers: A Single-Center, Phase I, Randomized, Four-Way Crossover Study. JOURNAL OF CLINICAL PHARMACOLOGY. pp. 75-86.

Brennan, MA, Gleeson, JP, O'Brien, FJ and McNamara, LM (2014) Effects of Ageing, Prolonged Estrogen Deficiency and Zoledronate on Bone Tissue Mineral Distribution. Journal of the Mechanical Behavior of Biomedical Materials, 29. pp. 161-170.

Briegel, A, Wong, ML, Hodges, HL, Oikonomou, CM, Piasta, KN, Harris, MJ, Fowler, DJ, Thompson, LK, Falke, JJ, Kiessling, LL and Jensen, GJ (2014) New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry. pp. 1575-1585.

Briggs, Katharine, Barber, Chris, Cases, Montse, Marc, Philippe and Steger-Hartmann, Thomas (2014) Value of shared preclinical safety studies – the eTOX database. Toxicology Reports.

Brigida, I, Sauer, AV, Ferrua, F, Giannelli, S, Scaramuzza, S, Pistoia, V, Castiello, MC, Barendregt, BH, Cicalese, MP, Casiraghi, M, Brombin, C, Puck, J, Muller, K, Notarangelo, LD, Montin, D, Van Montfrans, JM, Roncarolo, MG, Traggiai, E, Van Dongen, JJM, Van Der Burg, M and Aiuti, A (2014) B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients. Journal of Allergy and Clinical Immunology. pp. 799-806.

Bulliard, Yannick, Zhang, Jimin, Jolicoeur, Rose, Brogdon, Jennifer, Dranoff, Glenn and Wilson, Nicholas (2014) OX86 mediates depletion of OX40-expressing intratumoral regulatory T cells through Fc receptor co-engagement, leading to potent anti-tumor efficacy. OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy. pp. 1-6.

Bunzendahl, Sina, Basler, Anne, Kneuer, Rainer and Babu, Suresh (2014) Characterization of Small Immunoconjugates (< 40 kDa) Using Capillary Electrophoresis–Mass Spectrometry. Agilent Application Note .

Bush, CO, Pokrovskii, MV, Saito, R, Morganelli, P, Canales, E, Clarke, MO, Lazerwith, SE, Golde, J, Reid, BG, Babaoglu, K, Pagratis, N, Zhong, W, Delaney, WE, Paulson, MS and Beran, RKF (2014) A small-Molecule inhibitor of hepatitis C virus infectivity. Antimicrobial Agents and Chemotherapy. pp. 386-396.

Bushee, JL, Dunne, CE and Argikar, UA (2014) An in vitro approach to investigate ocular metabolism of a topical, selective beta1-adrenergic blocking agent, betaxolol. Xenobiotica. pp. 1-10.

Bushee, Jennifer, Liang, Guiqing, Dunne, Christine, Harriman, Shawn and Argikar, Upendra (2014) Identification of saturated and unsaturated fatty acids as microsomal degradation by-products by direct high resolution -ESI-MS/MS. Xenobiotica.

Butcher, Joshua, Stanley, Shyla, Brooks, Steven, Chantler, Paul, Wu, Fan and Frisbee, Jefferson (2014) IMPACT OF INCREASED INTRAMUSCULAR PERFUSION HETEROGENEITY ON SKELETAL MUSCLE MICROVASCULAR HEMATOCRIT IN THE METABOLIC SYNDROME. Microcirculation, 21 (8). pp. 677-687.

Cahill, JF, Darlington, TK, Wang, X, Mayer, J, Spencer, MT, Holecek, JC, Reed, BE and Prather, KA (2014) Development of a High-Pressure Aerodynamic Lens for Focusing Large Particles (4-10 mu m) into the Aerosol Time-of-Flight Mass Spectrometer. Aerosol Science and Technology. pp. 948-956.

Cai, Xinming, Xu, Yongyao, Kim, You-Me, Loureiro, Joe and Huang, Qian (2014) PIKfyve, a class III lipid kinase, is required for TLR-induced Type i IFN production via modulation of ATF3. Journal of Immunology, 192 (7). pp. 3383-3389. ISSN 1550-6606

Cao, F, Townsend, EC, Karatas, H, Xu, J, Li, L, Lee, S, Liu, L, Chen, Y, Ouillette, P, Zhu, J, Hess, JL, Atadja, P, Lei, M, Qin, ZS, Malek, S, Wang, S and Dou, Y (2014) Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia. MOLECULAR CELL. pp. 247-261.

Cao, James, Ying, Xiaoyou, Beyer, Bruce K. and Delise, Anthony (2014) The use of optical imaging to assess the potential for embryo-fetal exposure to an exogenous material after intravaginal administration. Reproductive Toxicology, 48. pp. 138-147.

Carnemolla, A, Labbadia, JP, Lazell, H, Neueder, A, Moussaoui, S and Bates, GP (2014) Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders. Hum Mol Genet . pp. 3641-3656.

Carter, Edward, Miron-Buchacra, G., Goldoni, Silvia, Danahay, Henry, Westwick , John, Watson, M.L., Tosh, David and Ward, Stephen (2014) Phosphoinositide 3-kinase alpha-dependent regulation of branching morphogenesis in murine embryonic lung: evidence for a role in determining morphogenic properties of FGF7. PLOS ONE.

Casas, J, Brzostek, J, Zarnitsyna, V, Hong, JS, Hoerter, J, Ampudia, J, Zamoyska, R, Zhu, C and Gascoigne, N (2014) Ligand engaged TCR is triggered by active Lck not associated with coreceptor. Nature Communications.

Cases, Montse, Briggs, Katharine, Steger-Hartmann, Thomas, Pognan, Francois, Marc, Philippe, Kleinöder, Thomas, Schwab, Christof H., Pastor, Manuel, Wichard, Joerg and Sanz, Ferran (2014) The eTOX data-sharing project to advance in silico drug-induced toxicity prediction. International Journal of Molecular Sciences, 15 (11). pp. 21136-21154.

Cavadini, Simone, Fischer, Eric, Goldie, Kenneth, Bohm, Kerstin, Lingaraju Gondichatnahalli, Manjappa, Jones, Matthew, Bunker, Richard, Faty, Mahamadou, Tichkule, Ritesh, Patelic, Radosav, Mohamed, Weaam, Hassiepen, Ulrich, Beckwith, Rohan, Stahlberg, Henning and Thomae, Nicolas (2014) Specificity, plasticity and regulation of cullin-RING ubiquitin E3 ligases by the COP9 signalosome. Nature.

Ceribelli, M, Kelly, PN, Shaffer, AL, Wright, GW, Xiao, W, Yang, Y, Griner, LAM, Guha, R, Shinn, P, Keller, JM, Liu, D, Patel, PR, Ferrer, M, Joshi, S, Nerle, S, Sandy, P, Normant, E, Thomas, CJ and Staudt, LM (2014) Blockade of oncogenic IB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors. Proceedings of the National Academy of Sciences of the United States of America. pp. 11365-11370.

Chan, JG, Tyne, AS, Pang, A, McLachlan, AJ, Perera, V, Chan, JC, Britton, WJ, Chan, HK, Duke, CC, Young, PM and Traini, D (2014) Murine pharmacokinetics of rifapentine delivered as an inhalable dry powder. International Journal of Antimicrobial Agents.

Chan, Stephen, Woollam, Grahame, Trixie, Wagner, Martin U., Schmidt and Lewis, Richard (2014) Can picolinamide be a promising cocrystal former? CrystEngComm, 16. pp. 4365-4368. ISSN 1466-8033

Chandriani, S, DePianto, DJ, N'Diaye, EN, Abbas, AR, Jackman, J, Bevers, IJ, Ramirez-Carrozzi, V, Pappu, R, Kauder, SE, Toy, K, Ha, C, Modrusan, Z, Wu, LC, Collard, HR, Wolters, PJ, Egen, JG and Arron, JR (2014) Endogenously expressed IL-13Ralpha2 attenuates IL-13- mediated responses but does not activate signaling in human lung fibroblasts. Journal of Immunology. pp. 111-119.

Chapman, Kathryn, Chivers, Simon, Gliddon, Dan, Mitchell, David, Robinson, Sally, Sangster, Tim, Sparrow, Susan, Spooner, Neil and Wilson, Amanda (2014) Overcoming the barriers to the uptake of nonclinical microsampling in regulatory safety studies. Drug Discovery Today, 19 (5). pp. 528-532. ISSN 1878-5832

Chapman, Victoria L, Zollinger, Tulipan, Terranova, Remi, Moggs, Jonathan, Kimber, Ian and Dearman, Rebecca (2014) Chemical allergen induced perturbations of the mouse lymph node DNA methylome. Toxicological Sciences, 139 (2). pp. 350-361. ISSN 1096-0929

Chen, G, Chakravarti, N, Aardalen, K, Lazar, AJ, Tetzlaff, MT, Wubbenhorst, B, Kim, SB, Kopetz, S, Ledoux, AA, Gopal, YN, Pereira, CG, Deng, W, Lee, JS, Nathanson, KL, Aldape, KD, Prieto, VG, Stuart, D and Davies, MA (2014) Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target. Clin Cancer Res . pp. 5537-5546.

Chen, Yen Liang, Abdul Ghafar, Nahdiyah, Karuna, Ratnaningrum, Fu, Yilong, Lim, Siew Pheng, Schul, Wouter, Gu, Feng, Yokokawa, Fumiaki, Wang, Gang, Cerny, Daniela, Fink, Katja, Blasco, Francesca and Shi, Pei-Yong (2014) Activation of PBMC by dengue virus infection depotentiates Balapiravir in dengue patients. Journal of Virology, 88 (3). pp. 1740-1747.

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Pastukhov, Oleksandr, Schwalm, Stephanie, Zangemeister-Wittke, Uwe, Fabbro, Doriano, Bornancin, Frederic, Japtok, Lukasz, Kleuser, Burkhard, Pfeilschifter, Josef and Huwiler, Andrea (2014) The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death. British Journal of Pharmacology, 171 (24). pp. 5829-5844. ISSN 1476-5381

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Patnaik, A, Weiss, GJ, Papadopoulos, KP, Hofmeister, CC, Tibes, R, Tolcher, A, Isaacs, R, Jac, J, Han, M, Payumo, FC, Cotreau, MM and Ramanathan, RK (2014) Phase i ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma. British Journal of Cancer. pp. 272-280.

Persson, BD, Jaffe, AB, Fearns, R and Danahay, H (2014) Respiratory Syncytial Virus Can Infect Basal Cells and Alter Human Airway Epithelial Differentiation. Plos One.

Peters, Eric, Sipila, Kalle, Haag, Sabrina, Denessiouk, Konstantin, Kapyla, Jarmo, Denesyuk, Alexander, Hansen, Uwe, Konttinen, Yrjo, Johnson, Mark, Holmdahl, Rikard and Heino, Jyrki (2014) Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner. FASEB Journal, 28 (8). pp. 3758-3768. ISSN 1530-6860

Peukert, Stefan, Hughes, Richard, Nunez, Jill, He, Guo, Yan , Zhao, Jain, Rishi, Llamas, Luis, Luchansky, Sarah, Carlson, Adam, Liang, Guiqing, Kunjathoor, Vidya, Pietropaolo, Michael, Shapiro, Jeffrey, Castellana, Anja, Wu, Xiaoping and Bose, Avirup (2014) Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists. ACS MedChemLetters.

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Phillips, Dean, Gao, Wenqi, Yang, Yang, Zhang, Guobao, Lerario, Isabelle, Lau, Thomas, Jiang, Jiqing, Wang, Xia, Nguyen, Deborah, Bhat, Barkur, Trotter, Carol, Welzel, Gustav, Sullivan, Heather, Landry, Jannine, Chen, Yali, Joseph, Sean, Li, Chun, Gordon, William, Richmond, Wendy, Johnson, Kevin, Bretz, Angela, Bursulaya, Badry, Pan, Shifeng, Mcnamara, Peter and Seidel, Martin (2014) Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: Structure-activity relationships, lead optimization, and chronic in vivo efficacy. Journal of Medicinal Chemistry, 57 (8). pp. 3263-3282. ISSN 1520-4804

Pierog, P, Krishna, M, Yamniuk, A, Chauhan, A and DeSilva, B (2014) Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples. Journal of Immunology Methods.

Pihl, Susanne, Michaut, Lydia, Hendriks, Jenny, Loebbert, Ralph, Ryding, Janka, Nemansky, Martin, Vermet, Laurent and Companjen, Arjen (2014) EBF Recommendation for stability testing of anti-drug antibodies; lessons learned from anti-vaccine antibody stability studies. Bioanalysis, 6 (10). pp. 1409-1413. ISSN 1757-6180

Pirard, Bernard and Ertl, Peter (2014) Evaluation of a Semi-Automated Workflow for Fragment Growing. Journal of Chemical Information and Modeling, 55 (1). pp. 180-193. ISSN 1549-960X

Pissani, F, Malherbe, DC, Schuman, JT, Robins, H, Park, BS, Krebs, SJ, Barnett, SW and Haigwood, NL (2014) Improvement of antibody responses by HIV envelope DNA and protein co-immunization. VACCINE. pp. 507-513.

Plappert Helbig, Ulla and Guérard , Melanie (2014) Inter-laboratory comparison of the in vivo comet assay including three image analysis systems. Environmental and Molecular Mutagenesis, 55 (2). pp. 114-121.

Plappert Helbig, Ulla, Van der Leede, Bas-jan, Doherty, Ann, Guérard, Melanie , Howe, Jonathan and Thybaud, Véronique (2014) Performance and data interpretation of the in vivo comet assay in pharmaceutical industry: EFPIA survey results. Current Topics in Genotoxicity Testing of Mutation Research – Genetic Toxicology and Environmental Mutagenesis, 775–77. pp. 81-88.

Poor, Stephen, Qiu, Yubin, Woolfenden, Amber, Fassbender, Elizabeth, Delpero, Andrea, Meredith, Erik, Buchanan, Natasha, Yong, kim, Hanks, Shawn, Shen, Siyuan, Gebuhr, Tom, Jaffee, Bruce and Dryja, Ted (2014) Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation. Investigations of Ophthalmic Visual Sciences.

Pop, MS, Stransky, N, Garvie, CW, Theurillat, JP, Hartman, EC, Lewis, TA, Zhong, C, Culyba, EK, Lin, F, Daniels, DS, Pagliarini, R, Ronco, L, Koehler, AN and Garraway, LA (2014) A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein. Mol Cancer Ther . pp. 1492-1502.

Portal, CF, Seifert, JM, Buehler, C, Meisner-Kober, NC and Auer, M (2014) Novel 1:1 Labeling and Purification Process for C-Terminal Thioester and Single Cysteine Recombinant Proteins Using Generic Peptidic Toolbox Reagents. BIOCONJUGATE CHEMISTRY. pp. 1213-1222.

Porter, David, Bradley, Michelle, Brown, Zarin, Canova, Riccardo, Charlton, Steven, Cox, Brian, Hunt, Peter, Kolarik, David, Lewis, Sarah, O'Connor, Des, Reilly, John, Spanka, Carsten, Tedaldi, Lauren, Watson, Simon, Wermuth, Roland and Press, Neil (2014) The Discovery of Potent, Orally Bioavailable Pyrazolo and Triazolopyrimidine CXCR2 Receptor Antagonists. Biorganic and Medicinal Chemistry Letters, 24 (1). pp. 72-76.

Porter, David, Bradley, Michelle, Brown, Zarin, Charlton, Steven, Cox, Brian, Hunt, Peter, Janus, Diana, Lewis, Sarah, Oakley, Paul, O'Connor, Des, Reilly, John, Smith, Nichola and Press, Neil (2014) The Discovery of Potent, Orally Bioavailable Pyrimidine-5-carbonitrile-6-alkyl CXCR2 Receptor Antagonists. Biorganic & Medicinal Chemistry Letters.

Portmann, T, Yang, M, Mao, R, Panagiotakos, G, Ellegood, J, Dolen, G, Bader, PL, Grueter, BA, Goold, C, Fisher, E, Clifford, K, Rengarajan, P, Kalikhman, D, Loureiro, D, Saw, NL, Zhengqui, Z, Miller, MA, Lerch, JP, Henkelman, RM, Shamloo, M, Malenka, RC, Crawley, JN and Dolmetsch, RE (2014) Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome. Cell reports.

Preuss, Inga, Ludwig, Marie-Gabrielle, Baumgarten, Birgit, Bassilana, Frederic, Gessier, Francois, Seuwen, Klaus and Sailer, Andreas (2014) Transcriptional regulation and functional characterization of the oxysterol / EBI2 system in primary human macrophages. Biochemical and Biophysical Research Communication, 446. pp. 663-668.

Proietti, M, Cornacchione, V, RezzonicoJost, T, Romagnani, A, Faliti, CE, Perruzza, L, Rigoni, R, Radaelli, E, Caprioli, F, Preziuso, S, Brannetti, B, Thelen, M, McCoy, KD, Slack, E, Traggiai, E and Grassi, F (2014) ATP-gated ionotropic P2X7 receptor controls follicular T helper cell numbers in peyer's patches to promote host-microbiota mutualism. Immunity. pp. 789-801.

Qi, H, Olson, CA, Wu, NC, Ke, R, Loverdo, C, Chu, V, Truong, S, Remenyi, R, Chen, Z, Du, Y, Su, S, Al-Mawsawi, LQ, Wu, T, Chen, S, Lin, C, Zhong, W, Lloyd-Smith, JO and Sun, R (2014) A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity. PLoS Pathogens.

Qiu, W, Rogers, AJ, Damask, A, Raby, BA, Klanderman, BJ, Duan, QL, Tyagi, S, Niu, S, Anderson, C, Cahir-Mcfarland, E, Mariani, TJ, Carey, V and Tantisira, KG (2014) Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis. Human Molecular Genetics. pp. 5017-5024.

Rahal, Rami, Frick, Mareike, Romero, Rodrigo, Ruddy, David, Derti, Adnan, Rakiec, Daniel, Naylor, Tara, Kauffmann, Audrey, Pfister-Wagner, Estelle, Fritsch, Christine, Kovats, Steven, Kim, Sunkyu, Dietze, Kerstin, Dorket, Bernd, Tzankov, Alexandar, Hummel, Michael, Monahan, John, Morrissey, Michael, Sellers, William, Lenz, Georg, Cooke, Vesselina, Bhang, Hyo-Eun, Farsidjani, Alireza, Hernandez-Ilizaliturri, Francisco J, Mavis, Cory and Stegmeier, Frank (2014) Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma. Nature Medicine, 20 (1). pp. 87-92. ISSN 1078-8956

Ramsden, Emma, Moulin, Pierre, Lee, David and Christ, Andreas Dominik (2014) QAX576, AN ANTI–INTERLEUKIN (IL)-13 MONOCLONAL ANTIBODY, FOR THE TREATMENT OF PATIENTS WITH FISTULISING CROHN’S DISEASE (CD): RESULTS OF A PROOF-OF-CONCEPT STUDY. United European Gastroenterology Week 2014.

Rascol, Olivier, Fox, Susan, Gasparini, Fabrizio, Kenney, Christopher, DiPaolo, Thérèse and Gomez-Mancilla, Baltazar (2014) Use of metabotropic glutamate 5-receptor antagonists for treatment of levodopa-induced dyskinesias. Parkinsonism and Related Disorders, 20 (9). pp. 947-956. ISSN 1873-5126

Ravenscroft, Neil, Cescutti, Paola, Stefanetti, Giuseppe, Londero, Silvia, Rondini, Simona and Maclennan, Calman Alexander (2014) Structural analysis of O-polysaccharide chains extracted from different Salmonella Typhimurium strains. Carbohydrate Research, 385. pp. 1-8. ISSN 1873-426X

Ravindran, Madhu Sudhan, Rao, Srinivasa P.S., Cheng, Xiamin, Shukla, Ankit, Cazenave-Gassiot, Amaury, Yao, Shao Q. and Wenk, Markus R. (2014) Targeting lipid esterases in mycobacteria grown under different physiological conditions using activity based profiling with tetrahydrolipstatin. Molecular & cellular proteomics : MCP, 13 (2). pp. 435-448. ISSN 1535-9484

Reck, Folkert (2014) Optimization of Physicochemical Properties and Safety Profile of Novel Bacterial Topoisomerase Type II Inhibitors (NBTIs) with activity against Pseudomonas aeruginosa. Optimization of Physicochemical Properties and Safety Profile of Novel Bacterial Topoisomerase Type II Inhibitors (NBTIs) with activity against Pseudomonas aeruginosa .

Repko, Brian (2014) "Big Data" Bioinformatics Models for Distributed, Parallel and Concurrent Processing. Slideshare / Twitter.

Reuter, Björn, Grudzenski, Saskia, Handwerker, E, Meairs, S, Heiler, P, Schad, L, Staufenbiel, Matthias, Hennerici, Michael P and Fatar, Marc (2014) Thrombolysis in experimental cerebral amyloid angiopathy and the risk of secondary intracerebral hemorrhage. Stroke, 45 (8). pp. 2411-2416. ISSN 0039-2499

Rieffel, Sebastien, Klopp, Julia, Roest, Susan, Carnal, Simon, Marti, Sabrina, Gerhartz, Bernd and Shrestha, Binesh (2014) Insect cell culture in reagent bottles. Insect cell culture in reagent bottles, 1. pp. 155-161. ISSN 2215-0161

Rieffel, Sebastien, Klopp, Julia, Roest, Susan, Carnal, Simon, Marti, Sabrina, Gerhartz, Bernd and Shrestha, Binesh (2014) Insect cell culture in reagent bottles. MethodsX, 1. pp. 155-161. ISSN 2215-0161

Rimann, Markus, Graf-Hausner, Ursula and Keller, Hansjoerg (2014) Bioprinting und in vitro Modelle zur Wirkstoffentwicklung. ZHAW transfer, 2014 (3). p. 5. ISSN none

Ringel, Frauke, Kaeda, Jaspal, Schwarz, Michaela, Oberender, Christian, Grille, Peggy, Doerken, Bernd, Marque, Fanny, Manley, Paul W., Radimerski, Thomas and le Coutre, Philippe (2014) Effects of the JAK2-selective inhibitors NVP-BSK805 and NVP-BVB808 in BCR-ABL or JAK2 mutation-positive cell lines. Haematologica, 132 (1). pp. 75-86. ISSN 1421-9662

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Thoma, Gebhard, Drueckes, Peter and Zerwes, Hans-Guenter (2014) Selective inhibitors of the Janus Kinase Jak3 – are they effective? Bioorganic & Medicibal Chemistry Letters, 24 (19). pp. 4617-4621. ISSN 0960894X

Thompson, Joel, Nagel, Jane, Hoving, Sjouke, Gerrits, Bertran, Bauer, Andreas, Thomas, Jason, Kirschner, Marc, Schirle, Markus and Luchansky, Sarah (2014) Quantitative Lys-ϵ-Gly-Gly (diGly) Proteomics Coupled with Inducible RNAi Reveals Ubiquitin-mediated Proteolysis of DNA Damage-inducible Transcript 4 (DDIT4) by the E3 Ligase HUWE1. The Journal of Biological Chemistry, 289 (42). pp. 28942-28955. ISSN 0021-9258

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Tian, Y, Voineagu, I, Pasca, SP, Won, H, Chandran, V, Horvath, S, Dolmetsch, RE and Geschwind, DH (2014) Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome. Genome Medicine. 75, 2014-.

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Toso, Alberto, Proietti, Michelle, Revandkar, Ajinkya, Zhang, Jiangwen, Guccini, Ilaria, Sarti, Manuela, Pinton, Sandra, Marini, Camilla, Scanziani, Eugenio, Catapano, Carlo, Pandolfi, Pier Paolo, Grassi, Fabio and Alimonti, Andrea (2014) Reactivation of senescence surveillance in Pten loss induced cellular senescence. Cell Reports.

Traeger, U, Andre, R, Lahiri, N, Magnusson-Lind, A, Weiss, A, Grueninger, S, McKinnon, C, Sirinathsinghji, E, Kahlon, S, Pfister, EL, Moser, R, Hummerich, H, Antoniou, M, Bates, GP, Luthi-Carter, R, Lowdell, MW, Bjoerkqvist, M, Ostroff, GR, Aronin, N and Tabrizi, SJ (2014) HTT-lowering reverses Huntington's disease immune dysfunction caused by NF kappa B pathway dysregulation. BRAIN. pp. 819-833.

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Trifilieff, Estelle, Minetti, Giulia, Sheppard, Kelly-Ann, Hatakeyama, Shinji, Feige, Jerome, Ibebunjo, Chikwendu, Feige, Jerome, Morvan, Frederic, Hartmann, Steffen, Rivet, Helene, Koelbing, Claudia and Glass, David (2014) An Antibody Blocking Activin Receptors type II Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy. Molecular and Cellular Biology.

Turner, Oliver, Morton, Dan, Sistare, Frank, Nambiar, Prashant, Zaher, Radi and Bower, Nancy (2014) Alternative Mouse Models for Future Cancer Risk Assessment. Toxicologic Pathology, 42 (5). pp. 1-8.

Ullrich, Thomas, Fernandes Gomes Dos Santos, Paulo Antonio, Perrone, Mark, Weiler, Sven, Keller, Hansjoerg, Sasmal, Sanjita, Boorgu, Venkatesham, Pasagadi, Srinivasu, Cheera, Srisailam, Rajagopalan, Sujatha , Bhumireddy, Archana, Shashikumar, Dhanya, Chelur, Shekar, Belliappa, Charamanna, Pandit, Chetan, Krishnamurthy, Narasimharao, Mukherjee, Subhendu, Ramanathan, Anuradha, Ghadiyaram, Chakshusmathi , Ramachandra, Murali, Lagu, Bharat and Bock, Mark G. (2014) 3-Alkoxy-pyrrolo[1,2-b]pyrazolines as novel selective androgen receptor modulators (SARMs) with physicochemical properties suitable for transdermal administration. Journal of Medicinal Chemistry, 57 (17). pp. 7396-7411. ISSN 0022-26231520-4804

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Vaupel, Andrea, Bold, Guido, Valat, Therese-Marie, Kallen, Joerg, Masuya, Keiichi, Furet, Pascal, de Pover, Alain and Hergovich-Lisztwan, Joanna (2014) Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction. Bioorganic and Medicinal Chemistry Letters, 24 (9). pp. 2110-2114. ISSN 0960894X

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Vliegenthart, A, Starkey Lewis, P, Tucker, C, Del Pozo, J, Rider, S, Antoine, D, Dubost, Valerie, Westphal, Magdalena, Moulin, Pierre, Bailey, M, Moggs, Jonathan, Goldring, C, Park, K and Dear, J (2014) Retro-orbital blood acquisition facilitates circulating microRNA measurement in zebrafish with paracetamol hepatotoxicity. Zebrafish, 11 (3). pp. 219-226. ISSN 1557-8542

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Weaver, Margaret (2014) Naphthoquine oral dose range finding study in the dog. This will be shared only with Kunming, not published..

Wegner, Malgorzata, Neddermann, Daniel, Piorunska-Stolzmann, Maria and Jagodzinski, Pawel (2014) Role of epigenetic mechanisms in the development of chronic complications of diabetes. Diabetes Research and Clinical Practice, 105 (2). pp. 164-175. ISSN 0168-8227

Wei, J, Freytag, M, Schober, Y, Nockher, WA, Mautner, VF, Friedrich, RE, Manley, PW, Kluwe, L and Kurtz, A (2014) Nilotinib is more potent than imatinib for treating plexiform neurofibroma in vitro and in vivo. PLoS ONE. e107760-.

Weidensteiner, Claudia, Allegrini, Peter Roland, Ferretti, Stephane Raymond and Mcsheehy, Paul M.J. (2014) Tumour T1 changes in vivo are highly predictive of response to chemotherapy and reflect the number of viable tumour cells. BMC cancer, 14. p. 88. ISSN 1471-2407

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Weiler, Sven, Braendlin, Nadine, Beerli, Christian, Bergsdorf, Christian, Schubart Wellensiek, Anna, Srinivas, Honnappa, Oberhauser, Berndt and Billich, Andreas (2014) Orally Active 7-Substituted (4-Benzyl-phthalazin-1-yl)-2-methyl-piperazin-1-yl]-nicotinonitriles as Active-site Inhibitors of Sphingosine-1-Phosphate Lyase for the Treatment of Multiple Sclerosis. Journal of Medicinal Chemistry, 57 (12). pp. 5074-5084. ISSN 0022-26231520-4804

Wendling, Thierry, Ogungbenro, Kayode, Pigeolet, Etienne, Dumitras, Swati, Woessner, Ralph and Aarons, Leon (2014) Model-based evaluation of the impact of formulation and food intake on the complex oral absorption of mavoglurant in healthy subjects. Pharmaceutical Research.

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Wilson, BG, Helming, KC, Wang, X, Kim, Y, Vazquez, F, Jagani, Z, Hahn, WC and Roberts, CWM (2014) Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation. MOLECULAR AND CELLULAR BIOLOGY. pp. 1136-1144.

Winkler, Gian Christian, Lovsin Barle, Ester, Galati, Giuseppe and Kluwe, William (2014) Functional differentiation of cytotoxic cancer drugs and targeted cancer therapeutics. Regulatory Toxicology and Pharmacology, on lin.

Wong, matthew H, Xue, Aiqun, Julovi, Sohel M, Pavlakis, Nick, Samra, Jas S, Hugh, Thomas J, Gill, Anthony J, Peters, Lyndsay, Baxter, Robert C and Smith, Ross C (2014) NVP-BYL719, a novel PI3K-alpha selective inhibitor, overcomes acquired erlotinib resistance via upregulation of the PI3K/Akt/ mTOR pathway in pancreatic ductal adenocarcinoma. Clinical Cancer Research.

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Wu, Bin, Guo, Fengfeng, Parmentier, Michael and Gallou, Fabrice (2014) Micelle enabled Hofmann Rearrangement in water. Organic process research & development. ISSN 1520-586X; 1083-6160

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Xia, B, Barve, A, Heimbach, T, Zhang, T, Gu, H, Wang, L, Einolf, H, Alexander, N, Hanna, I, Ke, J, Mangold, JB, He, H and Sunkara, G (2014) Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir. Eur J Pharm Sci . pp. 103-112.

Xiang, F, Murray, S and Liu, X (2014) Analysis of transplant urgency and benefit via multiple imputation. Stat Med .

Xie, Xuping, Lee, Le Tian, Chandrasekaran, Ramya, Reynaud, Aline, Wang, Qingyin, Dong, Hongping, Kang, Congbao, Yuan, Zhiming, Lescar, Julien and Shi, Pei-Yong (2014) Dimerization of flavivirus NS4B protein. Journal of Virology, 88 (6). pp. 3379-3391. ISSN 0022-538X

Xu, Haiyan, Shou, Jianyong and Li, En (2014) TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites. Cell research, 24 (8). pp. 1017-1020. ISSN 1748-7838

Xu, T, Yang, L, Yan, C, Wang, X, Huang, P, Zhao, F, Zhao, L, Zhang, M, Jia, W, Wang, X and Liu, Y (2014) The IRE1alpha-XBP1 pathway regulates metabolic stress-induced compensatory proliferation of pancreatic beta-cells. Cell research.

Yan, Jing-He, Meyers, Charles, Lee, Zachary, Danis, Kathryn, Neelakantham, Srikanth Raju, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar and Chen, Jin (2014) Pharmacokinetic and pharmacodynamic drug-drug interaction assessment between pradigastat and digoxin or warfarin. Journal of Clinical Pharmacology.

Yang, H, Lin, H, Xu, H, Zhang, L, Cheng, L, Wen, B, Shou, J, Guan, K, Xiong, Y and Ye, D (2014) TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites. Cell Res .

Yang, H, Robinson, M, Corsa, AC, Peng, B, Cheng, G, Tian, Y, Wang, Y, Pakdaman, R, Shen, M, Qi, X, Mo, H, Tay, C, Krawczyk, S, Sheng, XC, Kim, CU, Yang, C and Delaney IV, WE (2014) Preclinical characterization of the novel hepatitis C virus NS3 protease inhibitor GS-9451. Antimicrobial Agents and Chemotherapy. pp. 647-653.

Yang, Ziping (2014) Recommendations for Validation of LC-MS/MS Bioanalytical Methods for Protein Biotherapeutics. The AAPS Journal.

Yilmazel, B, Hu, YH, Sigoillot, F, Smith, JA, Shamu, CE, Perrimon, N and Mohr, SE (2014) Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. Bmc Bioinformatics.

Yu, DX, Di Giorgio, FP, Yao, J, Marchetto, MC, Brennand, K, Wright, R, Mei, A, McHenry, L, Lisuk, D, Grasmick, JM, Silberman, P, Silberman, G, Jappelli, R and Gage, FH (2014) Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports. pp. 295-310.

Yu, J, Sun, H, Pang, M, Chuang, W, Sarin, SK, Flisiak, R and Stein, DS (2014) Population pharmacokinetics and pharmacodynamics of albinterferon alfa-2b in patients treated for hepatitis C virus genotype 2/3. Anti-Infective Agents. pp. 58-67.

Yun Shan, Goh, Necchi, Francesca, O'Shaughnessy, Colette, Micoli, Francesca, Gavini, Massimiliano, Msefula, Chisomo, Gondwe, Esther, Mandala, Wilson, Gordon, Melita, Saul, Allan James and Maclennan, Calman Alexander (2014) HIV-associated bactericidal and inhibitory immunity to Salmonella in Africans. Journal of Immunology.

Zeiger, Errol , Gollapudi, Bhaskar, Aardema , Marilyn , Auerbach, Scott , Boverhof, Darrell, Custer, Laura, Dedon, Peter, Honma, Masamitsu, Ishida, Seiichi, Kasinski, Andrea, Kim, James, Manjanatha, Mugimane, Marlowe, Jenny, Pfuhler, Stefan, Pogribny, Igor, Slikker, William, Stankowski, Leon, Tanir, Jennifer, Tice, Raymond, van Benthem, Jan , White, Paul, Witt, Kristine and Thybaud, Veronique (2014) Genetic Toxicology: Opportunities to Integrate New Approaches. Environmental and Molecular Mutagenesis.

Zhang, JG, Ho, T, Callendrello, AL, Clark, RJ, Santone, EA, Kinsman, S, Xiao, D, Fox, LG, Einolf, HJ and Stresser, DM (2014) Evaluation of Calibration Curve-Based Approaches to Predict Clinical Inducers and Noninducers of CYP3A4 with Plated Human Hepatocytes. Drug Metab Dispos . pp. 1379-1391.

Zhang, Xian, Parker, Christian and Abraham, Yann (2014) Multiparametric Analysis of Screening Data: Growing Beyond the Single Dimension. Journal of Biomolecular Screening, 19 (5). pp. 628-639.

Zhang, Y, Chen, MH, Ibrahim, JG, Zeng, D, Chen, Q, Pan, Z and Xue, X (2014) Bayesian gamma frailty models for survival data with semi-competing risks and treatment switching. Lifetime Data Analysis. pp. 76-105.

Zhang, Yi-Xiang, Sicinska, Ewa, Czaplinski , Jeffrey, Remillard, Stephen, Moss, Samuel, Wang, Yuchuan, Brain, Christopher, Loo, Alice, Snyder, Eric, Demetri, George, Kim, Sunkyu, Kung, Andrew and Wagner, Andrew (2014) Antiproliferative effects of CDK4/6 inhibition in CDK4-amplified human liposarcoma in vitro and in vivo. Molecular Therapeutics.

Zhao, Nan, Zhao, Xia, Xu, Junyu, Zhao, Rong and Cui, Yimin (2014) 单次和多次口服氟伐他汀钠缓释片与速释胶囊人体药动学对比研究. The Chinese Journal of Clinical Pharmacology.

Zhou, Enhua, Watson, Christa, Pizzo, Richard , Cohen, Joel , Dang, Quynh , de Barros, Pedro Macul Ferreira, Park, Chan Young , Chen, Cheng , Brain, Joseph D. , Butler, James P. , Ruberti, Jeffrey W. , Fredberg, Jeffrey J. and Demokritou, Philip (2014) Assessing the impact of engineered nanoparticles on wound healing using a novel in-vitro bioassay. Nanomedicine, 9 (18). pp. 2803-2815. ISSN 1743-58891748-6963

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Zhu, J, Davoli, T, Perriera, JM, Chin, CR, Gaiha, GD, John, SP, Sigiollot, FD, Gao, G, Xu, Q, Qu, H, Pertel, T, Sims, JS, Smith, JA, Baker, RE, Maranda, L, Ng, A, Elledge, SJ and Brass, AL (2014) Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents. Cell Reports. pp. 752-766.

Zimmermann, MO, Lange, A, Wilcken, R, Cieslik, MB, Exner, TE, Joerger, AC, Koch, P and Boeckler, FM (2014) Halogen-enriched fragment libraries as chemical probes for harnessing halogen bonding in fragment-based lead discovery. Future Medicinal Chemistry. pp. 617-639.

Zollinger, Markus, Lozac'H, Frederic, Hurh, Eunju, Emotte, Corinne, Bauly, Hounayda and Swart, Pieter Jacob (2014) Absorption, distribution, metabolism, and excretion (ADME) of 14C-sonidegib (LDE225) in healthy volunteers. Cancer Chemotherapy and Pharmacology, 74 (1). pp. 63-75. ISSN 1432-0843

da Silva, A, Kronthaler, U, Koppenburg, V, Fink, M, Meyer, I, Papandrikopoulou, A, Hofmann, M, Stangler, T and Visser, J (2014) Target-directed development and preclinical characterization of the proposed biosimilar rituximab GP2013. LEUKEMIA & LYMPHOMA. pp. 1609-1617.

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This list was generated on Tue Nov 5 18:12:53 2024 UTC.

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