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Pastukhov, Oleksandr, Schwalm, Stephanie, Zangemeister-Wittke, Uwe, Fabbro, Doriano, Bornancin, Frederic, Japtok, Lukasz, Kleuser, Burkhard, Pfeilschifter, Josef and Huwiler, Andrea (2014) The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death. British Journal of Pharmacology, 171 (24). pp. 5829-5844. ISSN 1476-5381

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Patnaik, A, Weiss, GJ, Papadopoulos, KP, Hofmeister, CC, Tibes, R, Tolcher, A, Isaacs, R, Jac, J, Han, M, Payumo, FC, Cotreau, MM and Ramanathan, RK (2014) Phase i ficlatuzumab monotherapy or with erlotinib for refractory advanced solid tumours and multiple myeloma. British Journal of Cancer. pp. 272-280.

Persson, BD, Jaffe, AB, Fearns, R and Danahay, H (2014) Respiratory Syncytial Virus Can Infect Basal Cells and Alter Human Airway Epithelial Differentiation. Plos One.

Peters, Eric, Sipila, Kalle, Haag, Sabrina, Denessiouk, Konstantin, Kapyla, Jarmo, Denesyuk, Alexander, Hansen, Uwe, Konttinen, Yrjo, Johnson, Mark, Holmdahl, Rikard and Heino, Jyrki (2014) Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner. FASEB Journal, 28 (8). pp. 3758-3768. ISSN 1530-6860

Peukert, Stefan, Hughes, Richard, Nunez, Jill, He, Guo, Yan , Zhao, Jain, Rishi, Llamas, Luis, Luchansky, Sarah, Carlson, Adam, Liang, Guiqing, Kunjathoor, Vidya, Pietropaolo, Michael, Shapiro, Jeffrey, Castellana, Anja, Wu, Xiaoping and Bose, Avirup (2014) Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists. ACS MedChemLetters.

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Phillips, Dean, Gao, Wenqi, Yang, Yang, Zhang, Guobao, Lerario, Isabelle, Lau, Thomas, Jiang, Jiqing, Wang, Xia, Nguyen, Deborah, Bhat, Barkur, Trotter, Carol, Welzel, Gustav, Sullivan, Heather, Landry, Jannine, Chen, Yali, Joseph, Sean, Li, Chun, Gordon, William, Richmond, Wendy, Johnson, Kevin, Bretz, Angela, Bursulaya, Badry, Pan, Shifeng, Mcnamara, Peter and Seidel, Martin (2014) Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: Structure-activity relationships, lead optimization, and chronic in vivo efficacy. Journal of Medicinal Chemistry, 57 (8). pp. 3263-3282. ISSN 1520-4804

Pierog, P, Krishna, M, Yamniuk, A, Chauhan, A and DeSilva, B (2014) Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples. Journal of Immunology Methods.

Pihl, Susanne, Michaut, Lydia, Hendriks, Jenny, Loebbert, Ralph, Ryding, Janka, Nemansky, Martin, Vermet, Laurent and Companjen, Arjen (2014) EBF Recommendation for stability testing of anti-drug antibodies; lessons learned from anti-vaccine antibody stability studies. Bioanalysis, 6 (10). pp. 1409-1413. ISSN 1757-6180

Pirard, Bernard and Ertl, Peter (2014) Evaluation of a Semi-Automated Workflow for Fragment Growing. Journal of Chemical Information and Modeling, 55 (1). pp. 180-193. ISSN 1549-960X

Pissani, F, Malherbe, DC, Schuman, JT, Robins, H, Park, BS, Krebs, SJ, Barnett, SW and Haigwood, NL (2014) Improvement of antibody responses by HIV envelope DNA and protein co-immunization. VACCINE. pp. 507-513.

Plappert Helbig, Ulla and Guérard , Melanie (2014) Inter-laboratory comparison of the in vivo comet assay including three image analysis systems. Environmental and Molecular Mutagenesis, 55 (2). pp. 114-121.

Plappert Helbig, Ulla, Van der Leede, Bas-jan, Doherty, Ann, Guérard, Melanie , Howe, Jonathan and Thybaud, Véronique (2014) Performance and data interpretation of the in vivo comet assay in pharmaceutical industry: EFPIA survey results. Current Topics in Genotoxicity Testing of Mutation Research – Genetic Toxicology and Environmental Mutagenesis, 775–77. pp. 81-88.

Poor, Stephen, Qiu, Yubin, Woolfenden, Amber, Fassbender, Elizabeth, Delpero, Andrea, Meredith, Erik, Buchanan, Natasha, Yong, kim, Hanks, Shawn, Shen, Siyuan, Gebuhr, Tom, Jaffee, Bruce and Dryja, Ted (2014) Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation. Investigations of Ophthalmic Visual Sciences.

Pop, MS, Stransky, N, Garvie, CW, Theurillat, JP, Hartman, EC, Lewis, TA, Zhong, C, Culyba, EK, Lin, F, Daniels, DS, Pagliarini, R, Ronco, L, Koehler, AN and Garraway, LA (2014) A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein. Mol Cancer Ther . pp. 1492-1502.

Portal, CF, Seifert, JM, Buehler, C, Meisner-Kober, NC and Auer, M (2014) Novel 1:1 Labeling and Purification Process for C-Terminal Thioester and Single Cysteine Recombinant Proteins Using Generic Peptidic Toolbox Reagents. BIOCONJUGATE CHEMISTRY. pp. 1213-1222.

Porter, David, Bradley, Michelle, Brown, Zarin, Canova, Riccardo, Charlton, Steven, Cox, Brian, Hunt, Peter, Kolarik, David, Lewis, Sarah, O'Connor, Des, Reilly, John, Spanka, Carsten, Tedaldi, Lauren, Watson, Simon, Wermuth, Roland and Press, Neil (2014) The Discovery of Potent, Orally Bioavailable Pyrazolo and Triazolopyrimidine CXCR2 Receptor Antagonists. Biorganic and Medicinal Chemistry Letters, 24 (1). pp. 72-76.

Porter, David, Bradley, Michelle, Brown, Zarin, Charlton, Steven, Cox, Brian, Hunt, Peter, Janus, Diana, Lewis, Sarah, Oakley, Paul, O'Connor, Des, Reilly, John, Smith, Nichola and Press, Neil (2014) The Discovery of Potent, Orally Bioavailable Pyrimidine-5-carbonitrile-6-alkyl CXCR2 Receptor Antagonists. Biorganic & Medicinal Chemistry Letters.

Portmann, T, Yang, M, Mao, R, Panagiotakos, G, Ellegood, J, Dolen, G, Bader, PL, Grueter, BA, Goold, C, Fisher, E, Clifford, K, Rengarajan, P, Kalikhman, D, Loureiro, D, Saw, NL, Zhengqui, Z, Miller, MA, Lerch, JP, Henkelman, RM, Shamloo, M, Malenka, RC, Crawley, JN and Dolmetsch, RE (2014) Behavioral Abnormalities and Circuit Defects in the Basal Ganglia of a Mouse Model of 16p11.2 Deletion Syndrome. Cell reports.

Preuss, Inga, Ludwig, Marie-Gabrielle, Baumgarten, Birgit, Bassilana, Frederic, Gessier, Francois, Seuwen, Klaus and Sailer, Andreas (2014) Transcriptional regulation and functional characterization of the oxysterol / EBI2 system in primary human macrophages. Biochemical and Biophysical Research Communication, 446. pp. 663-668.

Proietti, M, Cornacchione, V, RezzonicoJost, T, Romagnani, A, Faliti, CE, Perruzza, L, Rigoni, R, Radaelli, E, Caprioli, F, Preziuso, S, Brannetti, B, Thelen, M, McCoy, KD, Slack, E, Traggiai, E and Grassi, F (2014) ATP-gated ionotropic P2X7 receptor controls follicular T helper cell numbers in peyer's patches to promote host-microbiota mutualism. Immunity. pp. 789-801.

Qi, H, Olson, CA, Wu, NC, Ke, R, Loverdo, C, Chu, V, Truong, S, Remenyi, R, Chen, Z, Du, Y, Su, S, Al-Mawsawi, LQ, Wu, T, Chen, S, Lin, C, Zhong, W, Lloyd-Smith, JO and Sun, R (2014) A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity. PLoS Pathogens.

Qiu, W, Rogers, AJ, Damask, A, Raby, BA, Klanderman, BJ, Duan, QL, Tyagi, S, Niu, S, Anderson, C, Cahir-Mcfarland, E, Mariani, TJ, Carey, V and Tantisira, KG (2014) Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis. Human Molecular Genetics. pp. 5017-5024.

Rahal, Rami, Frick, Mareike, Romero, Rodrigo, Ruddy, David, Derti, Adnan, Rakiec, Daniel, Naylor, Tara, Kauffmann, Audrey, Pfister-Wagner, Estelle, Fritsch, Christine, Kovats, Steven, Kim, Sunkyu, Dietze, Kerstin, Dorket, Bernd, Tzankov, Alexandar, Hummel, Michael, Monahan, John, Morrissey, Michael, Sellers, William, Lenz, Georg, Cooke, Vesselina, Bhang, Hyo-Eun, Farsidjani, Alireza, Hernandez-Ilizaliturri, Francisco J, Mavis, Cory and Stegmeier, Frank (2014) Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma. Nature Medicine, 20 (1). pp. 87-92. ISSN 1078-8956

Ramsden, Emma, Moulin, Pierre, Lee, David and Christ, Andreas Dominik (2014) QAX576, AN ANTI–INTERLEUKIN (IL)-13 MONOCLONAL ANTIBODY, FOR THE TREATMENT OF PATIENTS WITH FISTULISING CROHN’S DISEASE (CD): RESULTS OF A PROOF-OF-CONCEPT STUDY. United European Gastroenterology Week 2014.

Rascol, Olivier, Fox, Susan, Gasparini, Fabrizio, Kenney, Christopher, DiPaolo, Thérèse and Gomez-Mancilla, Baltazar (2014) Use of metabotropic glutamate 5-receptor antagonists for treatment of levodopa-induced dyskinesias. Parkinsonism and Related Disorders, 20 (9). pp. 947-956. ISSN 1873-5126

Ravenscroft, Neil, Cescutti, Paola, Stefanetti, Giuseppe, Londero, Silvia, Rondini, Simona and Maclennan, Calman Alexander (2014) Structural analysis of O-polysaccharide chains extracted from different Salmonella Typhimurium strains. Carbohydrate Research, 385. pp. 1-8. ISSN 1873-426X

Ravindran, Madhu Sudhan, Rao, Srinivasa P.S., Cheng, Xiamin, Shukla, Ankit, Cazenave-Gassiot, Amaury, Yao, Shao Q. and Wenk, Markus R. (2014) Targeting lipid esterases in mycobacteria grown under different physiological conditions using activity based profiling with tetrahydrolipstatin. Molecular & cellular proteomics : MCP, 13 (2). pp. 435-448. ISSN 1535-9484

Reck, Folkert (2014) Optimization of Physicochemical Properties and Safety Profile of Novel Bacterial Topoisomerase Type II Inhibitors (NBTIs) with activity against Pseudomonas aeruginosa. Optimization of Physicochemical Properties and Safety Profile of Novel Bacterial Topoisomerase Type II Inhibitors (NBTIs) with activity against Pseudomonas aeruginosa .

Repko, Brian (2014) "Big Data" Bioinformatics Models for Distributed, Parallel and Concurrent Processing. Slideshare / Twitter.

Reuter, Björn, Grudzenski, Saskia, Handwerker, E, Meairs, S, Heiler, P, Schad, L, Staufenbiel, Matthias, Hennerici, Michael P and Fatar, Marc (2014) Thrombolysis in experimental cerebral amyloid angiopathy and the risk of secondary intracerebral hemorrhage. Stroke, 45 (8). pp. 2411-2416. ISSN 0039-2499

Rieffel, Sebastien, Klopp, Julia, Roest, Susan, Carnal, Simon, Marti, Sabrina, Gerhartz, Bernd and Shrestha, Binesh (2014) Insect cell culture in reagent bottles. Insect cell culture in reagent bottles, 1. pp. 155-161. ISSN 2215-0161

Rieffel, Sebastien, Klopp, Julia, Roest, Susan, Carnal, Simon, Marti, Sabrina, Gerhartz, Bernd and Shrestha, Binesh (2014) Insect cell culture in reagent bottles. MethodsX, 1. pp. 155-161. ISSN 2215-0161

Rimann, Markus, Graf-Hausner, Ursula and Keller, Hansjoerg (2014) Bioprinting und in vitro Modelle zur Wirkstoffentwicklung. ZHAW transfer, 2014 (3). p. 5. ISSN none

Ringel, Frauke, Kaeda, Jaspal, Schwarz, Michaela, Oberender, Christian, Grille, Peggy, Doerken, Bernd, Marque, Fanny, Manley, Paul W., Radimerski, Thomas and le Coutre, Philippe (2014) Effects of the JAK2-selective inhibitors NVP-BSK805 and NVP-BVB808 in BCR-ABL or JAK2 mutation-positive cell lines. Haematologica, 132 (1). pp. 75-86. ISSN 1421-9662

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Thoma, Gebhard, Drueckes, Peter and Zerwes, Hans-Guenter (2014) Selective inhibitors of the Janus Kinase Jak3 – are they effective? Bioorganic & Medicibal Chemistry Letters, 24 (19). pp. 4617-4621. ISSN 0960894X

Thompson, Joel, Nagel, Jane, Hoving, Sjouke, Gerrits, Bertran, Bauer, Andreas, Thomas, Jason, Kirschner, Marc, Schirle, Markus and Luchansky, Sarah (2014) Quantitative Lys-ϵ-Gly-Gly (diGly) Proteomics Coupled with Inducible RNAi Reveals Ubiquitin-mediated Proteolysis of DNA Damage-inducible Transcript 4 (DDIT4) by the E3 Ligase HUWE1. The Journal of Biological Chemistry, 289 (42). pp. 28942-28955. ISSN 0021-9258

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Tian, Y, Voineagu, I, Pasca, SP, Won, H, Chandran, V, Horvath, S, Dolmetsch, RE and Geschwind, DH (2014) Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome. Genome Medicine. 75, 2014-.

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Toso, Alberto, Proietti, Michelle, Revandkar, Ajinkya, Zhang, Jiangwen, Guccini, Ilaria, Sarti, Manuela, Pinton, Sandra, Marini, Camilla, Scanziani, Eugenio, Catapano, Carlo, Pandolfi, Pier Paolo, Grassi, Fabio and Alimonti, Andrea (2014) Reactivation of senescence surveillance in Pten loss induced cellular senescence. Cell Reports.

Traeger, U, Andre, R, Lahiri, N, Magnusson-Lind, A, Weiss, A, Grueninger, S, McKinnon, C, Sirinathsinghji, E, Kahlon, S, Pfister, EL, Moser, R, Hummerich, H, Antoniou, M, Bates, GP, Luthi-Carter, R, Lowdell, MW, Bjoerkqvist, M, Ostroff, GR, Aronin, N and Tabrizi, SJ (2014) HTT-lowering reverses Huntington's disease immune dysfunction caused by NF kappa B pathway dysregulation. BRAIN. pp. 819-833.

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Trifilieff, Estelle, Minetti, Giulia, Sheppard, Kelly-Ann, Hatakeyama, Shinji, Feige, Jerome, Ibebunjo, Chikwendu, Feige, Jerome, Morvan, Frederic, Hartmann, Steffen, Rivet, Helene, Koelbing, Claudia and Glass, David (2014) An Antibody Blocking Activin Receptors type II Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy. Molecular and Cellular Biology.

Turner, Oliver, Morton, Dan, Sistare, Frank, Nambiar, Prashant, Zaher, Radi and Bower, Nancy (2014) Alternative Mouse Models for Future Cancer Risk Assessment. Toxicologic Pathology, 42 (5). pp. 1-8.

Ullrich, Thomas, Fernandes Gomes Dos Santos, Paulo Antonio, Perrone, Mark, Weiler, Sven, Keller, Hansjoerg, Sasmal, Sanjita, Boorgu, Venkatesham, Pasagadi, Srinivasu, Cheera, Srisailam, Rajagopalan, Sujatha , Bhumireddy, Archana, Shashikumar, Dhanya, Chelur, Shekar, Belliappa, Charamanna, Pandit, Chetan, Krishnamurthy, Narasimharao, Mukherjee, Subhendu, Ramanathan, Anuradha, Ghadiyaram, Chakshusmathi , Ramachandra, Murali, Lagu, Bharat and Bock, Mark G. (2014) 3-Alkoxy-pyrrolo[1,2-b]pyrazolines as novel selective androgen receptor modulators (SARMs) with physicochemical properties suitable for transdermal administration. Journal of Medicinal Chemistry, 57 (17). pp. 7396-7411. ISSN 0022-26231520-4804

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Vaupel, Andrea, Bold, Guido, Valat, Therese-Marie, Kallen, Joerg, Masuya, Keiichi, Furet, Pascal, de Pover, Alain and Hergovich-Lisztwan, Joanna (2014) Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction. Bioorganic and Medicinal Chemistry Letters, 24 (9). pp. 2110-2114. ISSN 0960894X

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Vliegenthart, A, Starkey Lewis, P, Tucker, C, Del Pozo, J, Rider, S, Antoine, D, Dubost, Valerie, Westphal, Magdalena, Moulin, Pierre, Bailey, M, Moggs, Jonathan, Goldring, C, Park, K and Dear, J (2014) Retro-orbital blood acquisition facilitates circulating microRNA measurement in zebrafish with paracetamol hepatotoxicity. Zebrafish, 11 (3). pp. 219-226. ISSN 1557-8542

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Weaver, Margaret (2014) Naphthoquine oral dose range finding study in the dog. This will be shared only with Kunming, not published..

Wegner, Malgorzata, Neddermann, Daniel, Piorunska-Stolzmann, Maria and Jagodzinski, Pawel (2014) Role of epigenetic mechanisms in the development of chronic complications of diabetes. Diabetes Research and Clinical Practice, 105 (2). pp. 164-175. ISSN 0168-8227

Wei, J, Freytag, M, Schober, Y, Nockher, WA, Mautner, VF, Friedrich, RE, Manley, PW, Kluwe, L and Kurtz, A (2014) Nilotinib is more potent than imatinib for treating plexiform neurofibroma in vitro and in vivo. PLoS ONE. e107760-.

Weidensteiner, Claudia, Allegrini, Peter Roland, Ferretti, Stephane Raymond and Mcsheehy, Paul M.J. (2014) Tumour T1 changes in vivo are highly predictive of response to chemotherapy and reflect the number of viable tumour cells. BMC cancer, 14. p. 88. ISSN 1471-2407

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Weiler, Sven, Braendlin, Nadine, Beerli, Christian, Bergsdorf, Christian, Schubart Wellensiek, Anna, Srinivas, Honnappa, Oberhauser, Berndt and Billich, Andreas (2014) Orally Active 7-Substituted (4-Benzyl-phthalazin-1-yl)-2-methyl-piperazin-1-yl]-nicotinonitriles as Active-site Inhibitors of Sphingosine-1-Phosphate Lyase for the Treatment of Multiple Sclerosis. Journal of Medicinal Chemistry, 57 (12). pp. 5074-5084. ISSN 0022-26231520-4804

Wendling, Thierry, Ogungbenro, Kayode, Pigeolet, Etienne, Dumitras, Swati, Woessner, Ralph and Aarons, Leon (2014) Model-based evaluation of the impact of formulation and food intake on the complex oral absorption of mavoglurant in healthy subjects. Pharmaceutical Research.

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Wilson, BG, Helming, KC, Wang, X, Kim, Y, Vazquez, F, Jagani, Z, Hahn, WC and Roberts, CWM (2014) Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation. MOLECULAR AND CELLULAR BIOLOGY. pp. 1136-1144.

Winkler, Gian Christian, Lovsin Barle, Ester, Galati, Giuseppe and Kluwe, William (2014) Functional differentiation of cytotoxic cancer drugs and targeted cancer therapeutics. Regulatory Toxicology and Pharmacology, on lin.

Wong, matthew H, Xue, Aiqun, Julovi, Sohel M, Pavlakis, Nick, Samra, Jas S, Hugh, Thomas J, Gill, Anthony J, Peters, Lyndsay, Baxter, Robert C and Smith, Ross C (2014) NVP-BYL719, a novel PI3K-alpha selective inhibitor, overcomes acquired erlotinib resistance via upregulation of the PI3K/Akt/ mTOR pathway in pancreatic ductal adenocarcinoma. Clinical Cancer Research.

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Wu, Bin, Guo, Fengfeng, Parmentier, Michael and Gallou, Fabrice (2014) Micelle enabled Hofmann Rearrangement in water. Organic process research & development. ISSN 1520-586X; 1083-6160

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Xia, B, Barve, A, Heimbach, T, Zhang, T, Gu, H, Wang, L, Einolf, H, Alexander, N, Hanna, I, Ke, J, Mangold, JB, He, H and Sunkara, G (2014) Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir. Eur J Pharm Sci . pp. 103-112.

Xiang, F, Murray, S and Liu, X (2014) Analysis of transplant urgency and benefit via multiple imputation. Stat Med .

Xie, Xuping, Lee, Le Tian, Chandrasekaran, Ramya, Reynaud, Aline, Wang, Qingyin, Dong, Hongping, Kang, Congbao, Yuan, Zhiming, Lescar, Julien and Shi, Pei-Yong (2014) Dimerization of flavivirus NS4B protein. Journal of Virology, 88 (6). pp. 3379-3391. ISSN 0022-538X

Xu, Haiyan, Shou, Jianyong and Li, En (2014) TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites. Cell research, 24 (8). pp. 1017-1020. ISSN 1748-7838

Xu, T, Yang, L, Yan, C, Wang, X, Huang, P, Zhao, F, Zhao, L, Zhang, M, Jia, W, Wang, X and Liu, Y (2014) The IRE1alpha-XBP1 pathway regulates metabolic stress-induced compensatory proliferation of pancreatic beta-cells. Cell research.

Yan, Jing-He, Meyers, Charles, Lee, Zachary, Danis, Kathryn, Neelakantham, Srikanth Raju, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar and Chen, Jin (2014) Pharmacokinetic and pharmacodynamic drug-drug interaction assessment between pradigastat and digoxin or warfarin. Journal of Clinical Pharmacology.

Yang, H, Lin, H, Xu, H, Zhang, L, Cheng, L, Wen, B, Shou, J, Guan, K, Xiong, Y and Ye, D (2014) TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites. Cell Res .

Yang, H, Robinson, M, Corsa, AC, Peng, B, Cheng, G, Tian, Y, Wang, Y, Pakdaman, R, Shen, M, Qi, X, Mo, H, Tay, C, Krawczyk, S, Sheng, XC, Kim, CU, Yang, C and Delaney IV, WE (2014) Preclinical characterization of the novel hepatitis C virus NS3 protease inhibitor GS-9451. Antimicrobial Agents and Chemotherapy. pp. 647-653.

Yang, Ziping (2014) Recommendations for Validation of LC-MS/MS Bioanalytical Methods for Protein Biotherapeutics. The AAPS Journal.

Yilmazel, B, Hu, YH, Sigoillot, F, Smith, JA, Shamu, CE, Perrimon, N and Mohr, SE (2014) Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. Bmc Bioinformatics.

Yu, DX, Di Giorgio, FP, Yao, J, Marchetto, MC, Brennand, K, Wright, R, Mei, A, McHenry, L, Lisuk, D, Grasmick, JM, Silberman, P, Silberman, G, Jappelli, R and Gage, FH (2014) Modeling hippocampal neurogenesis using human pluripotent stem cells. Stem Cell Reports. pp. 295-310.

Yu, J, Sun, H, Pang, M, Chuang, W, Sarin, SK, Flisiak, R and Stein, DS (2014) Population pharmacokinetics and pharmacodynamics of albinterferon alfa-2b in patients treated for hepatitis C virus genotype 2/3. Anti-Infective Agents. pp. 58-67.

Yun Shan, Goh, Necchi, Francesca, O'Shaughnessy, Colette, Micoli, Francesca, Gavini, Massimiliano, Msefula, Chisomo, Gondwe, Esther, Mandala, Wilson, Gordon, Melita, Saul, Allan James and Maclennan, Calman Alexander (2014) HIV-associated bactericidal and inhibitory immunity to Salmonella in Africans. Journal of Immunology.

Zeiger, Errol , Gollapudi, Bhaskar, Aardema , Marilyn , Auerbach, Scott , Boverhof, Darrell, Custer, Laura, Dedon, Peter, Honma, Masamitsu, Ishida, Seiichi, Kasinski, Andrea, Kim, James, Manjanatha, Mugimane, Marlowe, Jenny, Pfuhler, Stefan, Pogribny, Igor, Slikker, William, Stankowski, Leon, Tanir, Jennifer, Tice, Raymond, van Benthem, Jan , White, Paul, Witt, Kristine and Thybaud, Veronique (2014) Genetic Toxicology: Opportunities to Integrate New Approaches. Environmental and Molecular Mutagenesis.

Zhang, JG, Ho, T, Callendrello, AL, Clark, RJ, Santone, EA, Kinsman, S, Xiao, D, Fox, LG, Einolf, HJ and Stresser, DM (2014) Evaluation of Calibration Curve-Based Approaches to Predict Clinical Inducers and Noninducers of CYP3A4 with Plated Human Hepatocytes. Drug Metab Dispos . pp. 1379-1391.

Zhang, Xian, Parker, Christian and Abraham, Yann (2014) Multiparametric Analysis of Screening Data: Growing Beyond the Single Dimension. Journal of Biomolecular Screening, 19 (5). pp. 628-639.

Zhang, Y, Chen, MH, Ibrahim, JG, Zeng, D, Chen, Q, Pan, Z and Xue, X (2014) Bayesian gamma frailty models for survival data with semi-competing risks and treatment switching. Lifetime Data Analysis. pp. 76-105.

Zhang, Yi-Xiang, Sicinska, Ewa, Czaplinski , Jeffrey, Remillard, Stephen, Moss, Samuel, Wang, Yuchuan, Brain, Christopher, Loo, Alice, Snyder, Eric, Demetri, George, Kim, Sunkyu, Kung, Andrew and Wagner, Andrew (2014) Antiproliferative effects of CDK4/6 inhibition in CDK4-amplified human liposarcoma in vitro and in vivo. Molecular Therapeutics.

Zhao, Nan, Zhao, Xia, Xu, Junyu, Zhao, Rong and Cui, Yimin (2014) 单次和多次口服氟伐他汀钠缓释片与速释胶囊人体药动学对比研究. The Chinese Journal of Clinical Pharmacology.

Zhou, Enhua, Watson, Christa, Pizzo, Richard , Cohen, Joel , Dang, Quynh , de Barros, Pedro Macul Ferreira, Park, Chan Young , Chen, Cheng , Brain, Joseph D. , Butler, James P. , Ruberti, Jeffrey W. , Fredberg, Jeffrey J. and Demokritou, Philip (2014) Assessing the impact of engineered nanoparticles on wound healing using a novel in-vitro bioassay. Nanomedicine, 9 (18). pp. 2803-2815. ISSN 1743-58891748-6963

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Zhu, J, Davoli, T, Perriera, JM, Chin, CR, Gaiha, GD, John, SP, Sigiollot, FD, Gao, G, Xu, Q, Qu, H, Pertel, T, Sims, JS, Smith, JA, Baker, RE, Maranda, L, Ng, A, Elledge, SJ and Brass, AL (2014) Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents. Cell Reports. pp. 752-766.

Zimmermann, MO, Lange, A, Wilcken, R, Cieslik, MB, Exner, TE, Joerger, AC, Koch, P and Boeckler, FM (2014) Halogen-enriched fragment libraries as chemical probes for harnessing halogen bonding in fragment-based lead discovery. Future Medicinal Chemistry. pp. 617-639.

Zollinger, Markus, Lozac'H, Frederic, Hurh, Eunju, Emotte, Corinne, Bauly, Hounayda and Swart, Pieter Jacob (2014) Absorption, distribution, metabolism, and excretion (ADME) of 14C-sonidegib (LDE225) in healthy volunteers. Cancer Chemotherapy and Pharmacology, 74 (1). pp. 63-75. ISSN 1432-0843

da Silva, A, Kronthaler, U, Koppenburg, V, Fink, M, Meyer, I, Papandrikopoulou, A, Hofmann, M, Stangler, T and Visser, J (2014) Target-directed development and preclinical characterization of the proposed biosimilar rituximab GP2013. LEUKEMIA & LYMPHOMA. pp. 1609-1617.

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