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Highlights from the International Transporter Consortium (ITC) 2nd Workshop

Hoffmaster, Keith and Zamek-Gliszczynski, Maciej and Tweedie, Donald and Giacomini, Kathleen and Hillgren, Kathleen (2012) Highlights from the International Transporter Consortium (ITC) 2nd Workshop. Clinical Pharmacology and Experimental Therapeutics, 92 (5). pp. 553-556. ISSN 0009-92361532-6535

Abstract

The 2nd International Transporter Consortium workshop was held in March 2012 to expand upon previous whitepaper recommendations, discuss recent regulatory draft guidance documents on transporter-drug interactions, and highlight transporter-related challenges in drug development. The goal was to discuss additional clinically-relevant transporters (MATEs, MRP2, BSEP), best-practice methodologies, and re-evaluate ITC decision trees based upon actual case studies. The outcome of the workshop will be a series of whitepapers targeted for publication in 2013.

Item Type: Article
Keywords: Drug Transporters, Drug Interactions
Date Deposited: 26 Apr 2016 23:46
Last Modified: 26 Apr 2016 23:46
URI: https://oak.novartis.com/id/eprint/7921

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