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The Virtuous Technology Cycle Concept and its Application to Next Generation Sequencing

Pluess-Li, Ying and Bongiovanni, Sandrine and Oakeley, Edward James and Johnson, Keith and Staedtler, Frank (2012) The Virtuous Technology Cycle Concept and its Application to Next Generation Sequencing. Drug Discovery Today, 17 (17-18). pp. 1016-1022. ISSN 1359-6446

Abstract

External access to scientific technology plays an increasingly important role in pharmaceuticals. One advantage of accessing technology externally is to avoid the costs associated with purchase and the time required for the development of new methods; in addition, access to external scientific expertise can be beneficial. However, few conceptual frameworks exist for achieving an optimal mix of internal and external technology access. Here we describe the Virtuous Technology Cycle (VTC) concept and exemplify its application to Next-Generation Sequencing (NGS), which is seen as one of the most exciting and transformative technologies in molecular biology. Based on selected examples, we show that the VTC concept can greatly enhance the number of technologies accessed and thus significantly increase flexibility and efficiency in drug discovery. We also discuss the challenges of externally accessing NGS technologies.

Item Type: Article
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Additional Information: author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
Keywords: Virtuous technology cycle, paradox management, scientific technology outsourcing, next generation sequencing, drug discovery
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Date Deposited: 13 Oct 2015 13:14
Last Modified: 13 Oct 2015 13:14
URI: https://oak.novartis.com/id/eprint/7045

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