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1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents.

Coppola, Gary and Damon Ii, Robert and Eskesen, J and France, Dennis and Paterniti, James (2005) 1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents. Bioorganic & Medicinal Chemistry Letters, 15 (3). pp. 809-812. ISSN 0960-894X

Abstract

A series of 1-hydroxyalkyl-3-phenylthiourea analogs were prepared and evaluated as HDL-and Apo A-I-elevating agents. Derivatives 5h, 7j, 7n, and 7o were found to be as effective or superior to gemfibrozil.

Item Type: Article
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Additional Information: author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
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Date Deposited: 14 Dec 2009 13:55
Last Modified: 14 Dec 2009 13:55
URI: https://oak.novartis.com/id/eprint/693

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