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MRI in drug discovery

Allegrini, Peter Roland (2012) MRI in drug discovery. Eropean pharmaceutical review, 2012 (1).


MRI is in widespread use in clinical diagnosis as well as in research areas such as preclinical drug discovery. MRI allows non-invasive acquisition of tomographic images of animal soft tissue with high resolution and contrast. Furthermore its ability to assess organ function in a broad sense renders this technique to a versatile tool to answer specific scientific questions on the drug actions in disease models. Primarily imaging of patho-physiological mechanisms and molecular processes are in the focus of MRI in drug research. Finally MRI is translational and thus has the potential to bridge the gap between preclinical research on one hand and clinical development or therapy monitoring on the other.

Item Type: Article
Date Deposited: 13 Oct 2015 13:14
Last Modified: 13 Oct 2015 13:14