Dimnik, Ales (2025) The future of parenteral dosage forms manufacturing. Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia., 76 (3). pp. 193-201. ISSN 2536-4316

Abstract

The article provides a brief historical overview of parenteral pharmaceutical dosage forms production and discusses the fundamental requirements for their manufacturing. Further it focuses on expected future trends in production, such as the introduction of gloveless robotic systems in both industrial manufacturing and hospital pharmacies. Their implementation eliminates human intervention in aseptic environments, which represents the most critical aspect of parenteral pharmaceutical production. At the same time, adjustments in microbiological sampling within aseptic conditions can be expected. These adjustments reflect the need for the introduction of alternative rapid tests for microorganisms detection and a greater emphasis on monitoring critical process parameters that play a crucial role in ensuring the sterility of the entire batch of the pharmaceutical product. Among future directions, it is also important to highlight the continued expansion of the use of pre-sterilized primary packaging, prefilled syringes, and automatic dispensers.

Item Type:	Article
Keywords:	gloveless robotic systems, historical overview, parenteral dosage forms, rapid microbiological methods, trends
Date Deposited:	09 Aug 2025 00:45
Last Modified:	09 Aug 2025 00:45
URI:	https://oak.novartis.com/id/eprint/56210