Saldivia Concepcion, Manuel Alejandro, C A Lima, Ana Paula and Mottram, Jeremy (2024) A promising pipeline of preclinical drug candidates for leishmaniasis and chronic Chagas disease. Trends in parasitology, 40 (3). pp. 211-213. ISSN 14714922

Abstract

In recent years, the drug discovery pipeline for leishmaniasis and trypanosomiasis has been filling with a number of novel chemical entities (NCE) with known mechanisms of action (MoA). Recent work from González [1] and Braillard et al. [2] reports a Cytochrome bc1 complex inhibitor as another promising preclinical candidate for visceral leishmaniasis (VL) and in combination with a current drug, benznidazole, for chronic Chagas disease (CCD).

Item Type:	Article
Date Deposited:	09 Apr 2024 00:45
Last Modified:	09 Apr 2024 00:45
URI:	https://oak.novartis.com/id/eprint/53071