Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet) with concomitant administration of ketoconazole in healthy subjects.
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Lefevre, Gilbert, Carpenter, Polly, Souppart, Claire, Schmidli, Heinz, McClean, Mark and Stypinski, Daria (2002) Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet) with concomitant administration of ketoconazole in healthy subjects. British journal of clinical pharmacology, 54 (5). pp. 485-492. ISSN 0306-5251
Official URL: http://onlinelibrary.wiley.com/doi/10.1046/j.1365-...
Abstract
To evaluate whether the potent CYP3A4 inhibitor ketoconazole has any influence on the pharmacokinetic and electrocardiographic parameters of the antimalarial co-artemether (artemether-lumefantrine) in healthy subjects.
| Item Type: | Article |
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| Date Deposited: | 28 Jan 2012 00:45 |
| Last Modified: | 01 Feb 2013 00:47 |
| URI: | https://oak.novartis.com/id/eprint/5155 |