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Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis.

Revesz, Laszlo and Bollbuck, Birgit and Buhl, Thomas and Eder, Joerg and Esser, Ronald and Feifel, Roland and Heng, Richard and Hiestand, Peter and Jachez Demange, Benedicte and Loetscher, Pius and Sparrer, Helmut and Schlapbach, Achim and Waelchli, Rudolf (2005) Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis. Bioorganic & Medicinal Chemistry Letters, 15 (23). pp. 5160-5164. ISSN 0960-894X

Abstract

Cinnamides as novel CCR1 antagonist chemotypes are described with high affinity to human and rodent receptors. A1B1 and A4B7 showed oral activity in the mouse collagen induced arthritis.

Item Type: Article
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Additional Information: author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
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Date Deposited: 14 Dec 2009 13:58
Last Modified: 31 Jan 2013 01:15
URI: https://oak.novartis.com/id/eprint/500

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