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Multicellular dynamics of zonal liver regeneration mapped in space and time.

Tchorz, Jan and Feng, Chen (2022) Multicellular dynamics of zonal liver regeneration mapped in space and time. Cell stem cell, 29 (6). pp. 871-872. ISSN 1875-9777

Abstract

In this issue, Ben-Moshe et al. (2022) use spatiotemporally resolved single-cell and spatial transcriptomic profiling to dissect the multicellular dynamics enabling zonal liver regeneration. They highlight how pan-zonal compensatory hepatocyte proliferation, transient reprogramming of peri-injury hepatocytes, and concerted zonated action of different liver cell types orchestrate the healing process.

Item Type: Article
Keywords: Cell Proliferation Gene Expression Profiling Hepatocytes Liver Liver Regeneration Organogenesis
Date Deposited: 14 Aug 2025 00:45
Last Modified: 14 Aug 2025 00:45
URI: https://oak.novartis.com/id/eprint/47518

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