Multicellular dynamics of zonal liver regeneration mapped in space and time.
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Tchorz, Jan and Feng, Chen (2022) Multicellular dynamics of zonal liver regeneration mapped in space and time. Cell stem cell, 29 (6). pp. 871-872. ISSN 1875-9777
Official URL: https://pubmed.ncbi.nlm.nih.gov/35659871/
Abstract
In this issue, Ben-Moshe et al. (2022) use spatiotemporally resolved single-cell and spatial transcriptomic profiling to dissect the multicellular dynamics enabling zonal liver regeneration. They highlight how pan-zonal compensatory hepatocyte proliferation, transient reprogramming of peri-injury hepatocytes, and concerted zonated action of different liver cell types orchestrate the healing process.
Item Type: | Article |
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Keywords: | Cell Proliferation Gene Expression Profiling Hepatocytes Liver Liver Regeneration Organogenesis |
Date Deposited: | 14 Aug 2025 00:45 |
Last Modified: | 14 Aug 2025 00:45 |
URI: | https://oak.novartis.com/id/eprint/47518 |