Ogungbenro, Kayode, Matthews, Ivan, Looby, Michael, Kaiser, Guenther, Graham, Gordon and Aarons, Leon (2009) Population pharmacokinetics and optimal design of paediatric studies for famciclovir. British Journal of Clinical Pharmacology, 68 (4). pp. 546-560. ISSN 1365-2125

Abstract

To develop a population pharmacokinetic model for penciclovir (famciclovir is a prodrug of penciclovir) in adults and children and suggest an appropriate dose for children. Furthermore, to develop a limited sampling design based on sampling windows for three different paediatric age groups (1-2, 2-5 and 5-12 years) using an adequate number of subjects for future pharmacokinetic studies.

Item Type:	Article
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Date Deposited:	22 Jan 2011 00:45
Last Modified:	01 Feb 2013 00:47
URI:	https://oak.novartis.com/id/eprint/4280