Ruffner, Heinz and Aebi, Alexandra (2020) PhD Thesis: Technologies for Vascularized Skin Equivalents to Study Cutaneous Wound Healing in Vitro. PhD Thesis. ISSN NA

Abstract

PhD Thesis, Lisa Kiesewetter, "Technische Fakultät der Friedrich-Alexander-Universität Erlangen-Nürnberg zur Erlangung des Doktorgrades Dr.-Ing." University of Erlangen-Nürnberg, Germany.

Some of the work mentioned in the thesis are based on a Master Service Agreement of NIBR with the Fraunhofer Institute, dated August 14, 2015, aimed at a publication for the establishment of an in vitro skin model (exchange of protocols, reagents, positive control recombinant growth factor IGF-1). Due to lack of efficacy of the tested agents in the models, the data have not been submitted for publication. The NIBR contributions are mentioned on the following sections of the thesis:
Methods: pp. 66-67
Results: pp. 88-94
Discussion: pp. 151-152
Appendix: p. 203
Acknowledgements: p. 211

The two NVS employees mentioned below are acknowledged in the thesis, but they are not authors.

The models presented in this thesis should provide new, sophisticated alternatives for animal experiments in the field of research on cutaneous wound healing. Novel active pharmaceutical ingredients can be studied employing wound models meeting the specific experimental needs and biological complexity, while not solely restricted to biochemical and histological readout parameters.

Item Type:	Article
Keywords:	PhD Thesis
Date Deposited:	16 Jun 2020 00:45
Last Modified:	16 Jun 2020 00:45
URI:	https://oak.novartis.com/id/eprint/42592