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Embryonic stem cells: a great hope for a new era of medicine.

Tutter, Antonin V and Baltus, Gretchen A and Kadam, Shilpa (2006) Embryonic stem cells: a great hope for a new era of medicine. Current Opinion in Drug Discovery & Development, 9 (2). pp. 169-175. ISSN 1367-6733

Abstract

Current stem-cell research has the potential to lead to new approaches for the treatment of cardiovascular, neurodegenerative and musculoskeletal diseases, as well as diabetes and cancer. Stem-cell-based approaches could be employed in cell-replacement therapy or in drug treatments that encourage adult stem cells to migrate and activate at a site of injury or disease. For such therapeutic approaches to be successful, a greater understanding of the signaling pathways that determine the diverse developmental fates of these cells is needed. From a drug-discovery perspective, efforts are being deployed in developing cell-based assays to screen for small molecules that can modulate stem-cell fate. Such compounds will provide new insights into stem-cell biology, and may ultimately contribute to effective disease treatments.

Item Type: Article
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Additional Information: author can archive post-print (ie final draft post-refereeing); On a non-profit server
Keywords: Cancer; differentiation; embryonic; pluripotency; stem cell
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Date Deposited: 14 Dec 2009 14:00
Last Modified: 14 Dec 2009 14:00
URI: https://oak.novartis.com/id/eprint/420

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