Embryonic stem cells: a great hope for a new era of medicine.
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Tutter, Antonin V, Baltus, Gretchen A and Kadam, Shilpa (2006) Embryonic stem cells: a great hope for a new era of medicine. Current Opinion in Drug Discovery & Development, 9 (2). pp. 169-175. ISSN 1367-6733
Abstract
Current stem-cell research has the potential to lead to new approaches for the treatment of cardiovascular, neurodegenerative and musculoskeletal diseases, as well as diabetes and cancer. Stem-cell-based approaches could be employed in cell-replacement therapy or in drug treatments that encourage adult stem cells to migrate and activate at a site of injury or disease. For such therapeutic approaches to be successful, a greater understanding of the signaling pathways that determine the diverse developmental fates of these cells is needed. From a drug-discovery perspective, efforts are being deployed in developing cell-based assays to screen for small molecules that can modulate stem-cell fate. Such compounds will provide new insights into stem-cell biology, and may ultimately contribute to effective disease treatments.
| Item Type: | Article |
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| Additional Information: | author can archive post-print (ie final draft post-refereeing); On a non-profit server |
| Keywords: | Cancer; differentiation; embryonic; pluripotency; stem cell |
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| Date Deposited: | 14 Dec 2009 14:00 |
| Last Modified: | 14 Dec 2009 14:00 |
| URI: | https://oak.novartis.com/id/eprint/420 |