Browse views: by Year, by Function, by GLF, by Subfunction, by Conference, by Journal

Validating cancer drug targets.

Benson, John and Chen, Ying-Nan and Cornell-Kennon, Susan and Dorsch, Marion and Kim, Sunkyu and Leszczyniecka, Magdalena and Sellers, William and Lengauer, Christoph (2006) Validating cancer drug targets. Nature, 441 (7092). pp. 451-456. ISSN 1476-4687

Abstract

A cancer drug target is only truly validated by demonstrating that a given therapeutic agent is clinically effective and acts through the target against which it was designed. Nevertheless, it is desirable to declare an early-stage drug target as 'validated' before investing in a full-scale drug discovery programme dedicated to it. Although the outcome of validation studies can guide cancer research programmes, strictly defined universal validation criteria have not been established.

Item Type: Article
Related URLs:
Additional Information: author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
Related URLs:
Date Deposited: 14 Dec 2009 14:00
Last Modified: 31 Jan 2013 01:18
URI: https://oak.novartis.com/id/eprint/405

Search

Email Alerts

Register with OAK to receive email alerts for saved searches.