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Recent advances in the biology and therapy of muscle wasting

Glass, David and Roubenoff, Ronenn (2010) Recent advances in the biology and therapy of muscle wasting. Annals of the New York Academy of Sciences, 1211. pp. 25-36. ISSN 0077-8923


The recent advances in our understanding of the biology of muscle, and how anabolic and catabolic stimuli interact
to controlmusclemass and function, have led to new interest in pharmacological treatment ofmusclewasting. Loss of
muscle occurs as a consequence of many chronic diseases (cachexia), as well as normal aging (sarcopenia). Although
anabolic effects of exercise onmuscle have been know for many years, the development of pharmacological treatment
for muscle loss is in its infancy. However, there is a growing ferment in this field that may yield new treatments for
muscle wasting in the future.

Item Type: Article
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Additional Information: author can archive post-print (ie final draft post-refereeing); On personal web site or secure external website at authors institution; Publisher's version/PDF cannot be used
Keywords: cachexia, muscle, sarcopenia, treatment, anabolic
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Date Deposited: 13 Oct 2015 13:15
Last Modified: 13 Oct 2015 13:15


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