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Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.

Guery, Sebastien and Floersheim, Philipp and Kaupmann, Klemens and Froestl, Wolfgang (2007) Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors. Bioorganic & Medicinal Chemistry Letters, 17 (22). pp. 6206-6211. ISSN 0960-894X

Abstract

The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented.

Item Type: Article
Related URLs:
Additional Information: free final full text version available at PubMedCentral; author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
Keywords: GABAB positive allosteric modulators; GS39783; Drug addiction
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Date Deposited: 14 Dec 2009 14:01
Last Modified: 31 Jan 2013 01:18
URI: https://oak.novartis.com/id/eprint/372

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