Guery, Sebastien, Floersheim, Philipp, Kaupmann, Klemens and Froestl, Wolfgang (2007) Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors. Bioorganic & Medicinal Chemistry Letters, 17 (22). pp. 6206-6211. ISSN 0960-894X

Abstract

The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented.

Item Type:	Article
Related URLs:	http://www.ncbi.nlm.nih.gov/sites/entrez... http://www.pubmedcentral.nih.gov/article... doi:10.1016/j.bmcl.2007.09.023
Additional Information:	free final full text version available at PubMedCentral; author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
Keywords:	GABAB positive allosteric modulators; GS39783; Drug addiction
Related URLs:	http://www.ncbi.nlm.nih.gov/sites/entrez... http://www.pubmedcentral.nih.gov/article... doi:10.1016/j.bmcl.2007.09.023
Date Deposited:	14 Dec 2009 14:01
Last Modified:	31 Jan 2013 01:18
URI:	https://oak.novartis.com/id/eprint/372