Kingsley, Laura, Lelais, Gerald, Milliken, Kelly, Fuhs, Steve and Spraggon, Glen (2019) Development of a virtual reality platform for effective communication of structural data in drug discovery. Journal of Molecular Graphics and Modelling, 89. pp. 234-241. ISSN 18734243

Abstract

In drug discovery, structural knowledge of a target enables structure-based design approaches and thereby reduces the time and labor required to develop a therapy. Whilst molecular graphics frameworks coupled with computational analysis are now ubiquitous tools for the structural and computational biologist, sharing the detailed visualization and derived structural information with non-expert users still presents a challenge. Here we describe an intuitive virtual world for viewing, manipulating, and modifying chemical and macromolecular structures in a fully immersive and collaborative 3D environment. By reducing the barriers to viewing and interacting with structural data, structural analysis can be democratized to a general scientist, which in turn fosters novel collaboration, ideas, and findings in structural biology and structure-based drug discovery.

Item Type:	Article
Date Deposited:	07 May 2019 00:45
Last Modified:	07 May 2019 00:45
URI:	https://oak.novartis.com/id/eprint/36235