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One-pot synthesis of 2-aminobenzimidazoles using 2-chloro-1,3-dimethylimidazolinium chloride (DMC)

Artman Iii, Gerald and Solovay, Catherine and Adams, Christopher and Diaz, Brian and Dimitroff, Martin and Ehara, Takeru and Gu, Danlin and Ma, Fupeng and Liu, Donglei and Miller, Bridget Ranae and Pick, Teresa and Poon, Daniel and Ryckman, David and Siesel, David and Stillwell, Brady and Swiftney, Tyson and Van Dyck, Jonathan and Ji, Nan (2010) One-pot synthesis of 2-aminobenzimidazoles using 2-chloro-1,3-dimethylimidazolinium chloride (DMC). Tetrahedron Letters, 51 (40). pp. 5319-5321. ISSN 0040-4039

Abstract

2-Chloro-1,3-dimethylimidazolinium chloride (DMC or DMC-Cl) has been found to effectively and rapidly generate 2-aminobenzimidazoles from 1,2-diaminoarenes and isothiocyanates in moderate to good yields at room temperature in a one-pot operation.

Item Type: Article
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Date Deposited: 13 Oct 2015 13:16
Last Modified: 13 Oct 2015 13:16
URI: https://oak.novartis.com/id/eprint/3152

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