One-pot synthesis of 2-aminobenzimidazoles using 2-chloro-1,3-dimethylimidazolinium chloride (DMC)
Tools
Tools
Artman Iii, Gerald, Solovay, Catherine, Adams, Christopher, Diaz, Brian, Dimitroff, Martin, Ehara, Takeru, Gu, Danlin, Ma, Fupeng, Liu, Donglei, Miller, Bridget Ranae, Pick, Teresa, Poon, Daniel, Ryckman, David, Siesel, David, Stillwell, Brady, Swiftney, Tyson, Van Dyck, Jonathan and Ji, Nan (2010) One-pot synthesis of 2-aminobenzimidazoles using 2-chloro-1,3-dimethylimidazolinium chloride (DMC). Tetrahedron Letters, 51 (40). pp. 5319-5321. ISSN 0040-4039
Abstract
2-Chloro-1,3-dimethylimidazolinium chloride (DMC or DMC-Cl) has been found to effectively and rapidly generate 2-aminobenzimidazoles from 1,2-diaminoarenes and isothiocyanates in moderate to good yields at room temperature in a one-pot operation.
| Item Type: | Article |
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| Date Deposited: | 13 Oct 2015 13:16 |
| Last Modified: | 13 Oct 2015 13:16 |
| URI: | https://oak.novartis.com/id/eprint/3152 |