Ji, Wenzhi, Liu, Yahu and Liao, Xuebin (2016) Transition-Metal-Free Synthesis of N-Hydroxy Oxindoles by an Aza- Nazarov-Type Reaction Involving Azaoxyallyl Cations. Angewandte Chemie. International edition, 55 (n/a). pp. 13286-13289. ISSN 1521-3773; 0570-0833; 1433-7851

Abstract

Abstract: A novel transition-metal-free method to construct
N-hydroxy oxindoles by an aza-Nazarov-type reaction involving
azaoxyallyl cation intermediates is described. A variety of
functional groups were tolerated under the weak basic reaction
conditions and at room temperature. A one-pot process was
also developed to make the reaction even more practical. This
method provides alternative access to oxindoles and their
biologically active derivatives

Item Type:	Article
Date Deposited:	10 Nov 2016 00:45
Last Modified:	10 Nov 2016 00:45
URI:	https://oak.novartis.com/id/eprint/29144