Bouchez, Laure, Gerbeaux, Cyril, rusch, marion, Livendahl, madeleine, Patoor, Maude and Press, Neil (2016) Wake Up Call of A Sleeping Beauty”: Straightforward Synthesis of Functionalized β-(2-Pyridyl) Ketones from 2,6-Lutidine. Synlett.

Abstract

We report a one-step process for the preparation of substituted b-(2-pyridyl)-ketones with a variety of functional groups. b-(2-Pyridyl)-ketones are a unique class of heterocycle with valuable physicochemical properties and emerging pharmacophores. More specifically we exemplified the importance of this building block in a short series of anti-malarial natural products.

Item Type:	Article
Date Deposited:	17 Feb 2017 00:45
Last Modified:	17 Feb 2017 00:45
URI:	https://oak.novartis.com/id/eprint/28558