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Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome

Torene, Rebecca and Nirmala, Nanguneri and Obici, Laura and Meini, Antonella and Tormey, Vincent and Caorsi, R. and Starck-Schwertz, Sandrine and Letzkus, Martin and Hartmann, Nicole and Abrams, Ken and Lachmann, Helen and Gattorno, Marco (2016) Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome. Annals of the Rheumatic Diseases, 29. ISSN 1468-2060

Abstract

OBJECTIVE: To explore whether gene expression profiling can identify a molecular mechanism for the clinical benefit of canakinumab treatment in patents with tumour necrosis factor receptor-associated periodic syndrome (TRAPS).

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] ST - Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome [Field not mapped to EPrints] AU - Torene, R. [Field not mapped to EPrints] AU - Nirmala, N. [Field not mapped to EPrints] AU - Obici, L. [Field not mapped to EPrints] AU - Cattalini, M. [Field not mapped to EPrints] AU - Tormey, V. [Field not mapped to EPrints] AU - Caorsi, R. [Field not mapped to EPrints] AU - Starck-Schwertz, S. [Field not mapped to EPrints] AU - Letzkus, M. [Field not mapped to EPrints] AU - Hartmann, N. [Field not mapped to EPrints] AU - Abrams, K. [Field not mapped to EPrints] AU - Lachmann, H. [Field not mapped to EPrints] AU - Gattorno, M. [Field not mapped to EPrints] J2 - Ann Rheum Dis [Field not mapped to EPrints] AD - Torene,Rebecca. Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA. [Field not mapped to EPrints] M3 - Journal article [Field not mapped to EPrints] DB - MEDLINE [Field not mapped to EPrints] DP - Ovid Technologies [Field not mapped to EPrints] AN - 27474763 [Field not mapped to EPrints]
Date Deposited: 05 Dec 2016 00:45
Last Modified: 05 Dec 2016 00:45
URI: https://oak.novartis.com/id/eprint/27709

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