Walker, John and Hogenesch, John (2005) RNA profiling in circadian biology. Methods in Enzymology, 393. pp. 366-376. ISSN 1557-7988

Abstract

DNA arrays have become indispensable tools in the study of transcriptional output of the circadian clock and have enabled an increase in the number of outputs from tens to thousands. However, despite their widespread use, many challenges exist in accurately and sensitively identifying all transcriptional targets of the clock. This article discusses aspects of experimental design, including RNA-amplification strategies, data condensation methods, and other aspects that impact the use of these tools for the study of circadian biology.

Item Type:	Article
Related URLs:	http://www.ncbi.nlm.nih.gov/sites/entrez... doi:10.1016/S0076-6879(05)93016-4
Additional Information:	author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
Related URLs:	http://www.ncbi.nlm.nih.gov/sites/entrez... doi:10.1016/S0076-6879(05)93016-4
Date Deposited:	14 Dec 2009 14:02
Last Modified:	31 Jan 2013 01:22
URI:	https://oak.novartis.com/id/eprint/253