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European Bioanalysis Forum ‐ Recommendation on Dealing with Internal Standard Variability

Elbast, Walid, White, Stephen, Adcock, Neil, Hiller, Jim, Knutsson, Magnus, Lausecker, Berthold, Long, Jeff, McDougall, Stuart, Salavert, Fabrice, Sangster, Timothy, Verhaeghe, Tom and van Amsterdam, Peter (2014) European Bioanalysis Forum ‐ Recommendation on Dealing with Internal Standard Variability. Bioanalysis.

Abstract

Adequate monitoring of internal standard (IS) response across an analytical run and
identification of anomalies is now a common expectation. However, the means to conduct
this assessment in an appropriate manner is unclear and differs widely between
laboratories. A European Bioanalysis Forum (EBF) topic team was formed to survey current
practices within EBF member companies and to recommend a best practice approach to
industry for dealing with IS response variability.

Item Type: Article
Date Deposited: 31 May 2016 23:45
Last Modified: 31 May 2016 23:45
URI: https://oak.novartis.com/id/eprint/22885

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