A semipinacol rearrangement directed by an enzymatic system featuring dual-function FAD-dependent monooxygenase
Katsuyama, Yohei, Harmrolfs, Kirsten, Pistorius, Dominik, Li , Yanyan and Müller, Rolf (2012) A semipinacol rearrangement directed by an enzymatic system featuring dual-function FAD-dependent monooxygenase. Angewandte Chemie International Edition, 51 (37). pp. 9437-9440.
Abstract
Nature has invented ingenious ways to biosynthesize biologically active small molecules that have been applied ever since to benefit human life in various ways. During the underlying biosynthetic processes, highly elaborate chemical reactions are often catalyzed by enzymatic systems, thereby enabling transformations under physiological conditions that would require harsh conditions or are hardly possible without enzymatic catalysis. Consequently, understanding novel biochemical transformations is of importance to eventually apply the knowledge gained to generate molecules of interest.
Item Type: | Article |
---|---|
Date Deposited: | 13 Oct 2015 13:12 |
Last Modified: | 13 Oct 2015 13:12 |
URI: | https://oak.novartis.com/id/eprint/22866 |