Exo-Glycals: Versatile Intermediates in the Synthesis of 1,1-Disubstituted C Glycosides
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Woodward, Hannah, Smith, Nichola and Gallagher, Timothy (2010) Exo-Glycals: Versatile Intermediates in the Synthesis of 1,1-Disubstituted C Glycosides. Synlett (6). pp. 869-872. ISSN 0936-5214
Official URL: https://www.thieme-connect.com/ejournals/abstract/...
Abstract
The synthesis of 1,1-disubstituted C-glycosides 15, 18 and 21 containing amino and ester moieties at what is formally the anomeric site is described. Petasis olefination reaction of pyranosyl lactones 5-7 provided exo-glycals 8-10 which underwent regioselective azidoselenation and subsequent radical-mediated C-glycoside formation.
Item Type: | Article |
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Additional Information: | Author can archive post-print (ie final draft post-refereeing) subject to 12 month embargo on institutional repository; Publisher's version/PDF cannot be used |
Keywords: | C-glycosides; azidoselenation; Petasis olefination |
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Date Deposited: | 13 Oct 2015 13:16 |
Last Modified: | 13 Oct 2015 13:16 |
URI: | https://oak.novartis.com/id/eprint/2149 |