Recent advances in small molecule target identification methods
Tools
Tools
Tools
Jain, Rishi and Beckwith, Rohan (2013) Recent advances in small molecule target identification methods. Annual Reports in Medicinal Chemistry, 48. pp. 301-315. ISSN 0065-7743
Official URL: http://www.sciencedirect.com/science/article/pii/B...
Abstract
In this chapter, four major target identification approaches including affinity-based proteomics, in silico target prediction, drug resistance-sequencing, and yeast-based approaches are discussed with demonstrative examples from the last few years. © 2013 Elsevier Inc.
| Item Type: | Article |
|---|---|
| Keywords: | Affinity-based proteomics Chemical probes Drug resistance Haploinsufficiency profiling In silico target prediction Mechanism of action Phenotypic drug discovery Polypharmacology Target identification Yeast three hybrid |
| Date Deposited: | 23 Nov 2017 00:45 |
| Last Modified: | 25 Jan 2019 00:46 |
| URI: | https://oak.novartis.com/id/eprint/10027 |